Patents Assigned to Grifols, S.A.
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Patent number: 11905060Abstract: Method for the aseptic filling of a bag with a pharmaceutical product or liquid which comprises the following steps: a) a first step in which the cap is inserted in the inlet of the bag; b) a second step in which said cap is raised and the pharmaceutical product or liquid concerned is introduced; c) a third step in which the cap is re-inserted in the inlet of the bag; and d) a fourth step in which the cap and the inlet of the bag are welded.Type: GrantFiled: March 3, 2020Date of Patent: February 20, 2024Assignee: GRIFOLS, S.A.Inventors: Jordi Boira Bonhora, Miquel Faba Vilella, Daniel Fleta Coit
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Patent number: 11827403Abstract: Method for the aseptic filling of a bag with a pharmaceutical product or liquid which comprises the following steps: a) a first step in which the cap is inserted in the inlet of the bag; b) a second step in which said cap is raised and the pharmaceutical product or liquid concerned is introduced; c) a third step in which the cap is re-inserted in the inlet of the bag; and d) a fourth step in which the cap and the inlet of the bag are welded.Type: GrantFiled: March 3, 2020Date of Patent: November 28, 2023Assignee: GRIFOLS, S.A.Inventors: Jordi Boira Bonhora, Miquel Faba Vilella, Daniel Fleta Coit
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Patent number: 11807410Abstract: Device for labelling syringes for pharmaceutical products, comprising: means for feeding syringes to the device, a syringe manipulator configured to carry a syringe from the syringe-feeding means to the labelling station, a labelling station for labelling the syringes brought from the syringe-feeding means by means of the syringe manipulator, a control device for coordinating the aforementioned components, wherein the syringe-feeding means comprise a support for receiving a tray for holding one or more syringes, said support having a first position in which the syringe(s) on the tray is/are in a substantially vertical position.Type: GrantFiled: May 14, 2021Date of Patent: November 7, 2023Assignee: KIRO GRIFOLS, S.L.Inventors: Borja Lizari Illarramendi, Amaia Ilzarbe Andres, Brian Fernandez Alvarez, Patxi Urtzelai Aranbarri
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Patent number: 11738155Abstract: Device for handling a syringe and automated device for preparing intravenous medication comprising said device for handling a syringe The present invention discloses a device for handling a syringe, said syringe comprising a needle covered by a cap, said device comprising a main body which, in turn, comprises: a cap support comprising a housing for the cap of a needle, said housing being configured to hold said cap during removal and/or insertion of the needle from and/or into the cap by means of a linear movement; a device for joint removal of the cap and needle from the syringe by means of a rotation, comprising a slot defining two parallel faces spaced apart from each other and configured to interfere dimensionally with the cap of the syringe; at least one device for closing the syringe by means of a closed system transfer device (CSTD) or a cap, said device comprising a projection for fixing a support for said CSTD or cap, said support being replaceable and comprising a recess having a shape matching tType: GrantFiled: September 22, 2020Date of Patent: August 29, 2023Assignee: KIRO GRIFOLS, S.L.Inventors: Naiara Telleria Garay, Asier Lizarriturri Martiarena, Patxi Urtzelai Aranbarri
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Patent number: 11458070Abstract: A container for a solution of human plasma proteins has a primary inner bag made up of a first multilayer polymer film with two outer layers of polyethylene (PE) and an intermediate layer of ethylene vinyl alcohol (EVOH) copolymer, and a secondary outer bag made up of a second multilayer film with layers of polyethylene terephthalate (PET)-silicon oxides (SiOx), oriented polyamide (OPA), polypropylene (PP)-silicon oxides (SiOx) and polypropylene (PP), referred to as multilayer PP-SiOx.Type: GrantFiled: March 10, 2020Date of Patent: October 4, 2022Assignee: GRIFOLS, S.A.Inventors: Carlos Roura Fernandez, Jose Antonio Garcia Garcia, Estela Llorens Masas, Nuria Marzo Adam
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Patent number: 11337893Abstract: An adaptor for medical containers includes a hinge and a latch to attach the adaptor to respective support. The hinge includes a pivot to allow pivoting when a pivoting surface of the respective support and the pivot come in contact with each other. The adaptor can also include a zone for the reception of syringes, bags, vials and/or bottles.Type: GrantFiled: March 30, 2020Date of Patent: May 24, 2022Assignee: Kiro Grifols, S.L.Inventors: Borja Lizari Illarramendi, Ana Belen Barrio Jimenez, Amaia Ilzarbe Andres, Jose Ignacio Andres Pineda, Clara Molinuevo Portal, Pablo Lascurain Areitioaurtena
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Patent number: 11116765Abstract: Methods of treatment of NTM lung infections using formulations of liposomal ciprofloxacin. Specific liposome formulations and delivery of such for treatment of respiratory tract infections and other medical conditions, and devices and formulations used in connection with such are described.Type: GrantFiled: June 26, 2020Date of Patent: September 14, 2021Assignee: GRIFOLS, S.A.Inventors: Igor Gonda, James Blanchard, David C. Cipolla, Luiz Eduardo Moreira Bermudez
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Patent number: 11026941Abstract: A concentrated inhalable formulation of an antibiotic drug such as ciprofloxacin is disclosed. The antibiotic is formulated with sodium acetate and liposome which incorporate antibiotic. The formulation is aerosolized and inhaled for treatment of respiratory tract infections and other medical conditions.Type: GrantFiled: August 14, 2019Date of Patent: June 8, 2021Assignee: GRIFOLS, S.A.Inventors: David C. Cipolla, James Blanchard
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Patent number: 10926987Abstract: A device for placing threaded lids on containers includes a holder for lids to be placed and a mechanism for retaining the lids stored in the holder. The retaining mechanism has a predetermined retaining position in which the lids stored in the holder are retained and a release position in which one of the lids stored in the holder is dispensed. The device also includes a lid positioner, which places a threaded lid on a container through a first rotation about a first axis when the positioner is in the placing position. When the position is in the receiving position, the positioner causes the retaining mechanism to change from the predetermined retaining position to the release position through rotation about the first axis.Type: GrantFiled: July 17, 2017Date of Patent: February 23, 2021Assignee: Kiro Grifols, S.L.Inventors: Borja Lizari Illarramendi, Amaia Ilzarbe Andres, Jose Ignacio Andres Pineda, Clara Molinuevo Portal
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Publication number: 20200323845Abstract: Methods of treatment of NTM lung infections using formulations of liposoma ciprofloxacin. Specific liposome formulations and delivery of such for treatment of respiratory tract infections and other medical conditions, and devices and formulations used in connection with such are described.Type: ApplicationFiled: June 26, 2020Publication date: October 15, 2020Applicant: GRIFOLS, S.A.Inventors: Igor Gonda, James Blanchard, David C. Cipolla, Luiz Eduardo Moreira Bermudez
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Publication number: 20200309110Abstract: A method is for calibrating a peristaltic pump, and for dispensing a quantity of liquid by a peristaltic pump. A device for producing sterile preparations that can execute the methods.Type: ApplicationFiled: March 17, 2020Publication date: October 1, 2020Applicant: GRIFOLS, S.A.Inventors: Carles Xavier BELLONCH ORENES, David RODRIGUEZ JURADO, Ceferino RUZ TORRES, Ignacio BLAZQUEZ GARCIA-VALENZUELA, Xavier FERNANDEZ PEREZ
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Publication number: 20200297722Abstract: An aerosolizable formulation comprised of a drug, a carrier and pH affecting component is disclosed. The Drug is dissolved in the formulation at a concentration above which it remains in solution at neutral pH. This increases the concentration of the drug in solution making it possible to administer larger amounts of drug with the same or a smaller volume of formulation. When the formulation is aerosolized to small particles and inhaled into human lungs in small volumes (e.g. 0.05 to 0.5 mL) the fluids in the lungs neutralize the formulation causing the drug to participate out of solution. This results in the drug being delivered at a controlled rate below the rate at which drug is administered from a formulation initially at a neutral pH.Type: ApplicationFiled: June 8, 2020Publication date: September 24, 2020Applicant: GRIFOLS, S.A.Inventors: David C. Cipolla, Igor Gonda
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Publication number: 20200198820Abstract: Method for the aseptic filling of a bag with a pharmaceutical product or liquid which comprises the following steps: a) a first step in which the cap is inserted in the inlet of the bag; b) a second step in which said cap is raised and the pharmaceutical product or liquid concerned is introduced; c) a third step in which the cap is re-inserted in the inlet of the bag; and d) a fourth step in which the cap and the inlet of the bag are welded.Type: ApplicationFiled: March 3, 2020Publication date: June 25, 2020Applicant: GRIFOLS, S.A.Inventors: Jordi BOIRA BONHORA, Miquel FABA VILELLA, Daniel FLETA COIT
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Publication number: 20200198821Abstract: Method for the aseptic filling of a bag with a pharmaceutical product or liquid which comprises the following steps: a) a first step in which the cap is inserted in the inlet of the bag; b) a second step in which said cap is raised and the pharmaceutical product or liquid concerned is introduced; c) a third step in which the cap is re-inserted in the inlet of the bag; and d) a fourth step in which the cap and the inlet of the bag are welded.Type: ApplicationFiled: March 3, 2020Publication date: June 25, 2020Applicant: GRIFOLS, S.A.Inventors: Jordi BOIRA BONHORA, Miquel FABA VILELLA, Daniel FLETA COIT
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Patent number: 10654608Abstract: A labelling device for syringes for pharmaceutical products includes a carousel that holds and transports syringes, a syringe labelling station, a syringe handler, a camera for detecting the position of the marker scale of the syringes. The syringe labelling station includes an arm responsible for holding the label by a suction system and two articulated gates arranged such that when the syringe passes therethrough, the gates apply pressure over the body of the syringe in such a way that the label is affixed uniformly over the body.Type: GrantFiled: August 20, 2018Date of Patent: May 19, 2020Assignee: Kiro Grifols, S.L.Inventors: Borja Lizari Illarramendi, Susana Soto Iglesias, Asier Lizarriturri Martiarena, Amaia Ilzarbe Andres
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Patent number: 10646403Abstract: A device for loading medical containers on dosing machines includes an adaptor for medical containers and a support for the adaptor, in which the support includes an attachment means to the dosing machine and in which the adaptor and the support include means for pivoting relative to one another and means for clipping to each other. The means being arranged in such a way that the pivoting of the adaptor and of the support by means of the pivoting means produces the clipping together of the adaptor and the support.Type: GrantFiled: May 17, 2017Date of Patent: May 12, 2020Assignee: Kiro Grifols, S.L.Inventors: Borja Lizari Illarramendi, Ana Belen Barrio Jimenez, Amaia Ilzarbe Andres, Jose Ignacio Andres Pineda, Clara Molinuevo Portal, Pablo Lascurain Areitioaurtena
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Patent number: 10624814Abstract: A container for a solution of human plasma proteins has a primary inner bag made up of a first multilayer polymer film with two outer layers of polyethylene (PE) and an intermediate layer of ethylene vinyl alcohol (EVOH) copolymer, and a secondary outer bag made up of a second multilayer film with layers of polyethylene terephthalate (PET)-silicon oxides (SiOx), oriented polyamide (OPA), polypropylene (PP)-silicon oxides (SiOx) and polypropylene (PP), referred to as multilayer PP-SiOx.Type: GrantFiled: June 1, 2017Date of Patent: April 21, 2020Assignee: GRIFOLS, S.A.Inventors: Carlos Roura Fernandez, Jose Antonio Garcia Garcia, Estela Llorens Masas, Nuria Marzo Adam
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Patent number: 10625894Abstract: Method for the aseptic filling of a bag with a pharmaceutical product or liquid which comprises the following steps: a) a first step in which the cap is inserted in the inlet of the bag; b) a second step in which said cap is raised and the pharmaceutical product or liquid concerned is introduced; c) a third step in which the cap is re-inserted in the inlet of the bag; and d) a fourth step in which the cap and the inlet of the bag are welded.Type: GrantFiled: October 21, 2015Date of Patent: April 21, 2020Assignee: GRIFOLS, S.A.Inventors: Jordi Boira Bonhora, Miquel Faba Vilella, Daniel Fleta Coit
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Patent number: 10624924Abstract: A method and device for treating cholesterol disorders includes administering at least one treatment regime including two or more rounds of plasmapheresis to a patient having abnormal total cholesterol, abnormal LDL levels and/or abnormal HDL levels prior to treatment. Treatment according to the method results in decreased LDL levels in patients having abnormal LDL levels and increased HDL levels in patients having abnormal HDL levels. Each subsequent round of plasmapheresis is conducted weekly, but no more than twice per week.Type: GrantFiled: March 12, 2012Date of Patent: April 21, 2020Assignee: GRIFOLS, S.A.Inventors: Victor Grifols Lucas, Victor Grifols Roura
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Patent number: 10543941Abstract: A machine and a method are for the automatic preparation of substances for intravenous application. The machine includes a container receiving zone which defines a matrix of individual positions for initial and final containers, and a number of actuators for transferring substances from initial container to final container. Each of the actuators is positioned beneath the zone for receiving initial and final containers, each of the actuators is able to move relatively, independently of the rest of the actuators, and each of the actuators is suitable for receiving and operating injectors with different volumes and degrees of precision in order to remove substances from initial containers and insert them into final containers.Type: GrantFiled: April 19, 2016Date of Patent: January 28, 2020Assignee: Kiro Grifols, S.L.Inventors: Borja Lizari Illarramendi, Naiara Telleria Garay, Asier Lizarriturri Martiarena, Ana Belen Barrio Jimenez, Amaia Ilzarbe Andres, Jose Ignacio Andres Pineda