Patents Assigned to Grisotech S.A.
  • Patent number: 7189395
    Abstract: The present invention relates to complexes consisting of immunoglobulins and polysaccharides for oral and transmucosal use. The polysaccharides comprised in the complexes according to the invention form an envelope which protects and carries immunoglobulins allowing their systemic absorption through the gastric and mucosal district. Immunoglobulins have a different specificity depending on the required therapeutic effect. They are used in passive immunoprophylaxis for the prevention or therapy of infections caused by pathogenic agents such as virus, bacteria, parasites, or they are used in the modulation of endogenous bio-chemical balances, or in the detoxification from drugs of abuse, medicines, toxins.
    Type: Grant
    Filed: April 7, 2005
    Date of Patent: March 13, 2007
    Assignee: Grisotech S.A.
    Inventors: Rolando Wyss, Bernad Bizzini, Ivo Volpato
  • Patent number: 7186411
    Abstract: The main object of the present invention is to provide polysaccharide-coated antigens derivatised with lectins for pharmaceutical use. In the vaccines, polysaccharides are preferably selected from the group consisting of chitosan, low-molecular-weight and high-deacetylation-degree chitosan, methyl glycol. chitosan, alginic acid, polymannuronic acid and salts or derivatives thereof. In the vaccines of the invention, antigens are microorganisms, infectious agents or constituents thereof, hormones, enzymes, proenzymes, narcotics, bioactive peptides, metabolites, biological precursors, cell constituents, allergens, and the lectins are of vegetable origin.
    Type: Grant
    Filed: July 25, 2005
    Date of Patent: March 6, 2007
    Assignee: Grisotech S.A.
    Inventors: Rolando Wyss, Bernard Bizzini, Ivo Volpato
  • Patent number: 6936250
    Abstract: The main object of the present invention is to provide polysaccharide-coated antigens derivatized with lectins for pharmaceutical use. In the vaccines, polysaccharides are preferably selected from the group consisting of chitosan, low-molecular-weight and high-deacetylation-degree chitosan, methyl glycol chitosan, alginic acid, polymannuronic acid and salts or derivatives thereof. In the vaccines of the invention, antigens are microorganisms, infectious agents or constituents thereof, hormones, enzymes, proenzymes, narcotics, bioactive peptides, metabolites, biological precursors, cell constituents, allergens, and the lectins are of vegetable origin.
    Type: Grant
    Filed: March 18, 2002
    Date of Patent: August 30, 2005
    Assignee: Grisotech S.A.
    Inventors: Rolando Wyss, Bernad Bizzini, Ivo Volpato
  • Patent number: 6913746
    Abstract: The present invention relates to complexes consisting of immunoglobulins and polysaccharides for oral and transmucosal use. The polysaccharides comprised in the complexes according to the invention form an envelope which protects and carries immunoglobulins allowing their systemic absorption through the gastric and mucosal district. Immunoglobulins have a different specificity depending on the required therapeutic effect. They are used in passive immunoprophylaxis for the prevention or therapy of infections caused by pathogenic agents such as virus, bacteria, parasites, or they are used in the modulation of endogenous bio-chemical balances, or in the detoxification from drugs of abuse, medicines, toxins.
    Type: Grant
    Filed: February 20, 2002
    Date of Patent: July 5, 2005
    Assignee: Grisotech S.A.
    Inventors: Rolando Wyss, Bernad Bizzini, Ivo Volpato