Abstract: An aeroponic system for supporting efficient low-resource-usage plant growth comprises a housing comprising one or more openings and one or more root chambers; one or more sealing members configured to substantially conform to a stalk of a plant and to substantially isolate a canopy of the plant from the one or more root chambers; one or more root chamber sensors; one or more nutrient storage reservoirs for storage of plant nutrients; one or more air-assisted nozzles configured to introduce atomized nutrient solution into the one or more root chambers; a temperature control system configured to control a temperature of the one or more root chambers; and a control system configured to control the temperature control apparatus and the one or more air-assisted nozzles to maintain environmental parameters associated with the one or more root chambers within desired parameter ranges.