Patents Assigned to Gruppo Lepettit, S.P.A.
  • Process for the purification of proteins
    Patent number: 5981716
    Abstract: The present invention is directed to a simple and efficient process for the recovery of a biologically active glycoprotein from a biological fluid containing it.In a preferred embodiment, it comprises:a) contacting a filtered culture fluid with a dihydroxyboronyl bearing chromatographic supportb) eluting with a first eluting buffer and contacting this eluate directly with an anion exchange matrix bearing quaternary ammonium functional groupsc) eluting with a second eluting buffer and collecting the product therefrom.
    Type: Grant
    Filed: July 22, 1997
    Date of Patent: November 9, 1999
    Assignee: Gruppo Lepettit, S.P.A.
    Inventors: Dino Zanette, Edoardo Giacomo Sarubbi, Adolfo Soffientini, Ermenegildo Restelli, Armando Grigoletto