Abstract: In a dosimeter probe comprising a housing having two straps and including a cylindrical recess with a central extension a disc-like enclosure with an annular projection forming a circular cavity is disposed and a thermoluminescence detector is received in the cavity. At the open end of the cylindrical recess, the housing has an inwardly projecting annular flange structure which retains the enclosure in the recess and the enclosure is chamfered at the circumference of its disc portion for centering the enclosure with respect to the housing and facilitating insertion into the housing with a fit which provides for light-tight engagement between the enclosure and the housing walls.

Abstract: A hybrid fusion cell comprising:a) a malignant B cell which expresses an idiotypic antibody; andb) a hybridoma which expresses an antibody which is capable of being internalized on a professional antigen presenting cell.

Abstract: The present invention discloses a procedure for the destruction of contaminating tumor cells in stem cell transplants ex vivo using intact bispecific antibodies.

Abstract: In order to fulfill the requirements in terms of biological compatibility and mechanical stability, a transponder-holding case is provided as implant in animal breeding and keeping, which case consists of a first case section and a second case section made of a biologically compatible synthetic material, with the two case sections being designed for being detachably fastened at one another, preferably through a self-sealing and self-locking threaded joint, so as to form a hermetically sealed holding space for a transponder to be received therein. For an improvement of the position-retaining function in the animal body at least one of the case sections presents at least one formed-in portion on ist outside, and at least on the outside of one case section a receiving area is provided for a preferably laser-engraved identifier mark.

Abstract: In a method for reducing the content of heavy metals of solid materials, particularly of soils, a 0.1-10% aqueous solution of chemically modified biomasses of waste and residue materials is applied to the solid material whereby the heavy metals are released and extracted from the solid material. The biomass solution residues remaining in the solid material after the heavy metal extraction procedure is rapidly biodegradable so that no objectionable traces remain in the solid materials or soils.

Abstract: A pharmaceutical kit and process useful for achieving prolonged immunosuppression and tumor cell elimination, wherein the kit comprises a first antibody having binding specificity for T cells and is capable of eliminating T cells in vivo; and a second antibody, having binding specificity for T cells and is capable of eliminating T cells in vivo, capable of modulating the antigen effect of T cells or both, wherein said first antibody differs from said second antibody in the constant region of its heavy chains and thus belongs to a different animal species, wherein said first antibody and said second antibody are maintained separately in said kit, and wherein in said process said first antibody is first applied once or several times and said second antibody is applied at a different time from said first antibody.

Abstract: The present invention provides a process for the preparation of human monoclonal antibodies from human B cells. According to this process, human antibody-producing B cells are immortalized by infection with an Epstein-Barr virus, or derivative thereof, that expresses Epstein-Barr virus nuclear antigen 2 (EBNA2). EBNA2 function, which is required for immortalization, is subsequently shut off, which results in an increase in antibody production. The invention provides a variety of systems that allow expression of EBNA2 function to achieve immortalization, followed by reduction of EBNA2 expression or function to facilitate antibody production.

Abstract: A method and composition are described for the treatment of mammalian HIV infections including administering an effective subtoxic dosage of melittin (Seq. ID NO:1) to the mammal whereby the growth of HIV infected cells or the replication of the virus in the infected cells of the mammal is inhibited.

Abstract: A human bone marrow stromal cell line, which is characterized in that the cells of the cell line, after irradiation which results in the growth being arrested, remain adherent, is suitable for use as a feeder layer for supporting the proliferation of blood cells.

Abstract: In a method of extracting royal jelly from comb cells of queens, workers, and drones of Apis mellifera, the royal jelly is extracted under an inert gas cover such that it does not come into contact with air in the process, whereby the properties of the royal jelly are consistently retained.