Abstract: The present disclosure relates to a system for neuromodulation and/or neurostimulation, for the treatment of a subject. The system comprises a stimulation controller, a stimulation pattern storage means including stimulation data connected to the stimulation controller, an electrical stimulation device and electrical interface between the electrical stimulation device and the subject, the electrical interface being connectable with a bio-interface of the nervous system of the subject. The stimulation data are pre-programmed patterns comprising spatial and temporal components, The stimulation controller sends configuration signals on the basis of the stimulation data to the electrical stimulation device such that via the electrical interface electrical stimulation is provided to the bio-interface, wherein the electrical stimulation provided is characterized by stimulation parameters that vary over time in a pre-programmed manner.

Abstract: The present disclosure relates to an active closed-loop medical system comprising at least one implantable medical device, at least one non-implanted component and at least a controller for controlling the implantable medical device, wherein the implantable medical device, the non-implanted component and the controller are connected for data exchange, wherein the implantable medical device, the non-implanted component and the controller forming in the active state a closed-loop system in such that the implantable medical device is controlled by the controller on the basis of the signals exchanged with the non-implanted component.

Abstract: The present disclosure relates to a pulse generating system comprising a pulse generator for generating a pulse or pulses and a controller for controlling the pulse generating means, where the pulse generating system is capable to work in at least a regular mode and a safety mode, where in the regular mode the pulse generator and the controller are connected and where in the safety mode there is no connection between the pulse generator and the controller and where in the safety mode the pulse generator automatically switches to a baseline stimulation command.