Abstract: The present invention discloses a method for safe production of rice on soil mildly and moderately polluted by heavy metals. The method includes applying a passivator before transplanting rice seedlings to reduce activity of heavy metals in soil, and then spraying a foliar barrier from the peak tillering stage to the booting stage of rice and at the filling stage of rice; the passivator includes bentonite, gypsum powder, lime, a biochar, an iron-based biochar, a slow-release iron-based biochar, an iron-sulfur-silicon composite biochar, a heavy metal cadmium passivator and a cadmium-arsenic synchronous passivator for activating sulfur reducing bacteria in paddy soil; and the foliar barrier includes an acid silica sol, a selenium-silicon composite sol, a cerium composite silica sol, a ferrous modified selenium sol. The method can also include applying a nitrate nitrogen fertilizer at the seedling stage of rice, and/or applying a phosphorus potassium fertilizer at the tillering stage of rice.