Patents Assigned to GUANGDONG PROVINCIAL HOSPITAL OF TRADITIONAL CHINESE MEDICINE
  • Application of obacunone in preparation of drug for preventing and treating lung damage and pulmonary fibrosis
    Patent number: 10632100
    Abstract: Disclosed is application of obacunone in the manufacture of a medicament for prevention or treatment of lung injury and pulmonary fibrosis. The medicament consists of obacunone and pharmaceutically acceptable auxiliaries and additives, wherein obacunone is 3% to 25% by mass in the medicament. The obacunone in the medicament can inhibit bleomycin-induced lung injury and pulmonary fibrosis in mice, and regulate the expression of the inflammation-associated cytokines in the bleomycin-induced injured lung tissue in mice.
    Type: Grant
    Filed: February 28, 2017
    Date of Patent: April 28, 2020
    Assignee: GUANGDONG PROVINCIAL HOSPITAL OF TRADITIONAL CHINESE MEDICINE
    Inventors: Yang Xu, Shengmei Xu, Weimin Chen
  • APPLICATION OF OBACUNONE IN PREPARATION OF DRUG FOR PREVENTING AND TREATING LUNG DAMAGE AND PULMONARY FIBROSIS
    Publication number: 20190046502
    Abstract: Disclosed is application of obacunone in the manufacture of a medicament for prevention or treatment of lung injury and pulmonary fibrosis. The medicament consists of obacunone and pharmaceutically acceptable auxiliaries and additives, wherein obacunone is 3% to 25% by mass in the medicament. The obacunone in the medicament can inhibit bleomycin-induced lung injury and pulmonary fibrosis in mice, and regulate the expression of the inflammation-associated cytokines in the bleomycin-induced injured lung tissue in mice.
    Type: Application
    Filed: February 28, 2017
    Publication date: February 14, 2019
    Applicant: GUANGDONG PROVINCIAL HOSPITAL OF TRADITIONAL CHINESE MEDICINE
    Inventors: Yang XU, Shengmei XU, Weimin CHEN