Abstract: The present disclosure relates to a composition capable of promoting hair growth, including a pulchinenoside active component of pulchinenoside B4 or pulchinenoside B5. The experiment results are showed that the composition of the present disclosure can promote hair growth in a hair removal area of mice, improve its growth speed and increase the number of hair follicles, and has non-toxic side effects, low cost and rapid curative effect. The present disclosure also discloses a drug capable of promoting hair growth, including a pulchinenoside active component of pulchinenoside B4 or pulchinenoside B5. The present disclosure also discloses pulchinenoside B4 or pulchinenoside B5 as an active component in preparation of the composition or drug capable of promoting hair growth.

Abstract: The present disclosure relates to an application of anemoside B4 in preparation of drug for treatment or prevention of psoriasis. Anemoside B4 has therapeutic effect on 5% imiquimod-induced psoriatic lesions in mice. Its possible mechanism may be inhibiting inflammation reactions, regulating immune function and inhibiting angiogenesis, and the therapeutic effect may be realized by inhibiting the release of IL-12, IL-17, IL-6 and IL-1? in skin tissue. This study of the present disclosure laid a theoretical foundation for the subsequent development of anemoside B4 into an anti-psoriasis drug of traditional Chinese medicine.