Abstract: The present invention is directed to a flowable hemostatic paste comprising a crosslinked carboxymethyl cellulose and at least one non-toxic dispersant. More specifically the present invention relates to a hemostatic paste containing citric acid cross-linked CMC, which is suspended or dispersed as a powder in a mixture of a first non-toxic glycerol-containing hygroscopic dispersant and a second non-toxic alcohol functionalized dispersant comprising propylene glycol or 1,3-butanediol.
Type:
Grant
Filed:
March 21, 2022
Date of Patent:
November 21, 2023
Assignees:
Guangzhou Bioseal Co., Ltd., Johnson & Johnson China Ltd., Ethicon, Inc.
Abstract: The present invention is directed to a flowable hemostatic paste comprising a crosslinked carboxymethyl cellulose and at least one non-toxic dispersant. More specifically the present invention relates to a hemostatic paste containing citric acid cross-linked CMC, which is suspended or dispersed as a powder in a mixture of a first non-toxic glycerol-containing hygroscopic dispersant and a second non-toxic alcohol functionalized dispersant comprising propylene glycol or 1,3-butanediol.
Type:
Grant
Filed:
June 25, 2020
Date of Patent:
August 16, 2022
Assignees:
Guangzhou Bioseal Co., Ltd., Johnson & Johnson China Ltd., Ethicon Inc.