Patents Assigned to Guidotti Internationale S.A.
  • Method for the manufacture of the cis-2-hydroxy-2-phenyl-r-1-cyclohexanecarboxylic acid
    Patent number: 4125558
    Abstract: A known effective choleretic, cis-2-hydroxy-2-phenyl-r-1-cyclohexane carboxylic acid is obtained with a novel method wherein 1-phenylcyclohexene is reacted with formaldehyde in formic acid or mixture of formic acid with other solvents. The reaction mixture is hydrolyzed (alkaline hydrolysis) to provide a substituted cyclohexanol concurrently with a substituted dioxan. The substituted diol is separated from the substituted dioxan and finally oxidized to obtain the expected acid.
    Type: Grant
    Filed: November 8, 1976
    Date of Patent: November 14, 1978
    Assignee: Guidotti Internationale S.A.
    Inventor: Cosimo B. Torsi