Patents Assigned to Gull Laboratories
  • Methods and apparatus for detection and discrimination of multiple analytes using flourescent technology
    Patent number: 5861256
    Abstract: The present invention provides methods and apparatus for detecting and discriminating multiple analytes within a test sample which are rapid, accurate, and convenient enough for routine use in a clinical laboratory. In particular, the present invention provides methods and apparatus for permitting multiple PCR-amplified target nucleic acid sequence hybrids within a single sample, labeled with different fluorescent dyes, to be spectrally distinguished using the read-out data directly from a fluorescence reader instrument.
    Type: Grant
    Filed: September 8, 1997
    Date of Patent: January 19, 1999
    Assignee: Gull Laboratories
    Inventors: Michael J. Glass, Jana Coombs, Sharon L. Malmstrom, Linxian Wu
  • Methods and apparatus for preparing, amplifying, and discriminating multiple analytes
    Patent number: 5846783
    Abstract: The present invention provides methods and apparatus for detecting and discriminating multiple analytes within a test sample which are simple, user-friendly, cost-effective and fast. In particular, it is preferred that the overall time for sample preparation, nucleic acid sequence amplification, and nucleic acid sequence differentiation be about 5 hours or less.
    Type: Grant
    Filed: August 6, 1996
    Date of Patent: December 8, 1998
    Assignee: Gull Laboratories
    Inventors: Linxian Wu, Jana Coombs, Sharon L. Malmstrom, Michael J. Glass
  • Methods for detection and discrimination of multiple analytes using fluorescent technology
    Patent number: 5723294
    Abstract: The present invention provides methods and apparatus for detecting and discriminating multiple analytes within a test sample which are rapid, accurate, and convenient enough for routine use in a clinical laboratory. In particular, the present invention provides methods and apparatus for permitting multiple PCR-amplified target nucleic acid sequence hybrids within a single sample, labeled with different fluorescent dyes, to be spectrally distinguished using the read-out data directly from a fluorescence reader instrument.
    Type: Grant
    Filed: March 5, 1996
    Date of Patent: March 3, 1998
    Assignee: Gull Laboratories
    Inventors: Michael J. Glass, Jana Coombs, Sharon L. Malmstrom, Linxian Wu
  • Methods, kits and solutions for preparing sample material for nucleic acid amplification
    Patent number: 5612473
    Abstract: The present invention provides methods and apparatus for detecting and discriminating multiple analytes within a test sample which are simple, user-friendly, cost-effective and fast. In particular, it is preferred that the overall time for sample preparation, nucleic acid sequence amplification, and nucleic acid sequence differentiation be about 5 hours or less.
    Type: Grant
    Filed: January 16, 1996
    Date of Patent: March 18, 1997
    Assignee: Gull Laboratories
    Inventors: Linxian Wu, Jana Coombs, Sharon L. Malmstrom, Michael J. Glass