Abstract: The present invention is directed to the compounds of Formula I which are inhibitors of tropomyosin-related kinase A (TrkA): Formula (I) or stereoisomers, tautomers or a pharmaceutically acceptable salts, metabolites, isotopes, solvates or prodrugs thereof, wherein, Ra, Rb, Rc, Rd, R1, R2, L and Het-Ar are as defined herein.
Type:
Grant
Filed:
January 22, 2016
Date of Patent:
July 2, 2019
Assignee:
GVK BIOSCIENCES PRIVATE LIMITED
Inventors:
Kumaragurubaran Nagaswamy, Vijaya G. Tirunagaru
Abstract: The present invention is directed to the compounds of Formula I which are inhibitors of tropomyosin-related kinase A (TrkA): Formula (I) or steroisomers, tautomers or a pharmaceutically acceptable salts, metabolites, isotopes, solvates or prodrugs thereof, wherein, Ra, Rb, Rc, Rd, R1, R2, L and Het-Ar are as defined herein.
Type:
Application
Filed:
January 22, 2016
Publication date:
January 11, 2018
Applicant:
GVK BIOSCIENCES PRIVATE LIMITED
Inventors:
Kumaragurubaran Nagaswamy, Vijaya G. Tirunagaru