Abstract: The invention relates to a method for dosing a target component (20), wherein a dosing system (10) doses the target component (20) to a target value (Z20), which corresponds to a desired nominal value (S20soll), wherein an additional dosing system (12) doses at least one additional component (21, 22, 23) to be follow-on dosed, to a target value (Z21) of the component (21, 22, 23) to be follow-on dosed which is lower than a desired nominal value (S21soll) of the component (21, 22, 23) to be follow-on dosed, wherein an actual value (G20ist) of the target component (20) and at least one actual value (G21ist) of the component (21, 22, 23) to be follow-on dosed are then determined, a content (A) of the target component (20) then being calculated according to the actual value (G20ist) of the target component (20) and/or the actual value (G21ist) of the component (21, 22, 23) to be follow-on dosed and the content (A) being compared to a limit value (T) or tolerance band (T), at least the component (21, 22, 23) to be

Abstract: The invention relates to a distributor device, to a method for guiding materials, and to a method for cleaning a distributor device. The distributor device for guiding materials, in particular particulate pharmaceutical solids, comprises: a process chamber (2) having at least one inlet opening (3) and having at least two outlet openings (4), a distributor element (5) for distributing the materials, wherein the distributor element (5) extends through the process chamber (2) in order to connect the inlet opening (3) to one of the outlet openings (4), wherein the distributor element (5) is arranged rotatably about an axis of rotation (6), and a cleaning apparatus (7) which is configured to clean the process chamber (2) and the distributor element (5).

Abstract: A drum coater device (10) for coating tablets, comprising a mixing drum (18) which can be rotated about an axis of rotation (20) and which has an interior (24) for arranging a tablet batch to be coated, further comprising a spraying device for introducing a coating material into the interior, wherein the mixing drum has a hollow-cylindrical, perforated wall which delimits at least part of the interior of the mixing drum, wherein mixing elements for mixing the tablets of a tablet batch are arranged on the inner side, which faces the interior, of the wall, wherein pairs (36) of mixing elements (34a, 34b) form legs which are oriented with respect to one another in a V shape, wherein the distance between the legs of a pair widens from a central annular region, as seen along the axis of rotation, of the wall in the direction of lateral annular regions adjacent to the central annular region.

Abstract: A production module for producing solid medicaments in individual batches, comprising a supplying device for supplying powdered starting materials, a mixing device connected to the feeding device and is intended for working the supplied powdered starting materials into a product, a final working device connected to the mixing device and is intended for the final production of an end product from the worked starting materials, and a control device for automatically controlling the supplying device and the mixing device and the final working device. Diverters allow a batch to be passed on from the supplying device to the mixing device and from the mixing device to the final working device without any backmixing. Data of all the process sensors and quality sensors of the production module are linked with the respective batch by the control device such that tracking and tracing of the batches is made possible.

Abstract: The invention relates to a fluidised bed system (1) comprising a plurality of granulation units (2), arranged so as to be functionally parallel, for producing pharmaceutical granules, each granulation unit (2) comprising: a fluidised bed container (3), an inlet (4) and an outlet (5) on said fluidised bed container (3), a fluid supply (6) and a fluid discharge (7) on said fluidised bed container (3), and at least one injection nozzle (8) for injecting a processing substance into the fluidised bed container (3), as well as a control unit for adjusting processing conditions within each granulation unit (2).

Abstract: A filter arrangement, for cleaning gases contaminated with particles, has at least one filter unit with an exterior and an interior filter (3.1, 3.2), wherein the exterior and interior filters can be moved relative to each other, thereby exposing an opening (3.4) in the bottom regions thereof. This allows cleaning of filter units at the site of the filter units without disassembly of the same (cleaning in place—CIP). A method for cleaning is provided in that the region of the filter unit on the clean gas side including introducing a fluid sprayed via a cleaning lance protruding into the clean gas region while exposing a gap (3.4) in the bottom region of the exterior and interior filters.