Abstract: The present invention relates to methods kits and combined compositions using DFO-metal complexes, specifically, Zinc-desferrioxamine (Zn-DFO), gallium-desferrioxamine (Ga-DFO) complexes and any combinations thereof for preventing, treating, ameliorating or inhibiting an immune-related disorder, specifically, a skin-related inflammatory disorder such as psoriasis, an inflammatory respiratory condition such as asthma, and an autoimmune disease such as diabetes and any immune-related disorder.

Abstract: The present invention provides an article, at least part of it being coated by inorganic fullerene-like (IF) nanoparticles or composite containing such nanoparticles. Preferably, the invention provides an article made of metal, for use in dentistry or medicine e.g. archwire, needle or catheter, having a friction-reducing film, and methods for coating such articles with a friction-reducing film.

Abstract: The present invention relates to a method for the diagnosis of a neurodegenerative disorder in a mammalian subject. The method of the invention comprises the steps of (a) providing a body fluid sample of said subject; (b) concentrating proteins comprised within said sample by a suitable means; (c) contacting the concentrated sample obtained in step (b) with a sufficient amount of a protein which has a beta-sheet structure, preferably, an IgG light chain, under conditions suitable to allow the formation of aggregates. Which aggregates comprise a protein associated with a neurodegenerative disorder, and (d) measuring aggregate formation by suitable means. Whereby the presence of aggregates in said sample indicates that said subject carries said neurodegenerative disorder. The invention further provides for kits and diagnostic compositions for the detection of a neurodegenerative disorder, particularly, prion diseases.

Abstract: A brace for correction of scoliosis is disclosed, comprising at least one thoracic shell element and a pelvic shell element and at least one working element having a main longitudinal axle to be oriented parallel to the trunk to be treated, anchored on one of its opposite ends to the thoracic shell element and on the other to the pelvic shell element, and having spring characteristics adapted to apply continuous de-rotational force about said longitudinal axle.