Abstract: The present invention relates to a pharmaceutical composition for preventing or treating cancer, which contains a glucose uptake inhibitor and a sesquiterpene lactone. The pharmaceutical composition according to the present invention is capable of effectively inhibiting the proliferation of not only cancer cells but also cancer stem cells, thereby preventing and/or treating cancer, and furthermore, preventing the resistance, metastasis and recurrence of cancer.

Abstract: The present invention relates to a composition for effectively treating cancer stem cells, and more specifically to a composition for treating cancer stem cells, which contains a glucose uptake inhibitor, a biguanide-based compound, and a calcium pump inhibitor. The composition of the present invention can be used as an agent of treating cancer stem cells by effectively inducing apoptosis of the cancer stem cells. Accordingly, the composition of the present invention can be used as a pharmaceutical composition capable of effectively treating various cancer stem cells to effectively inhibiting cancer recurrence and/or metastasis.