Patents Assigned to HAISCO PHARMACEUTICALS PTE. LTD.
  • NITRILE DERIVATIVE THAT ACTS AS INHIBITOR OF DIPEPTIDYL PEPTIDASE 1 AND USE THEREOF
    Publication number: 20240059681
    Abstract: Disclosed is a nitrile derivative compound represented by formula (I), a stereoisomer, a deuterated product, a co-crystal, a solvate or a pharmaceutically acceptable salt thereof, wherein each group is as defined in the description. The compound has dipeptidyl peptidase 1 inhibitory activity and can be used to prepare a drug for treating diseases including obstructive airway diseases, bronchiectasis, cystic fibrosis, asthma, emphysema, and chronic obstructive pulmonary diseases.
    Type: Application
    Filed: September 15, 2023
    Publication date: February 22, 2024
    Applicant: HAISCO PHARMACEUTICALS PTE. LTD.
    Inventors: Yao Li, Zongjun Shi, Guobiao ZHANG, Lei Chen, Wenjing Wang, Xiaobo Zhang, Dengyu Zheng, Bo Xu, Xin Liu, Yajun Wang, Fei Ye, Pingming Tang, Jia Ni, Chen Zhang, Pangke Yan
  • SALT OF COMPOUND FOR DEGRADING BTK, CRYSTAL FORM THEREOF, AND USE THEREOF IN MEDICINE
    Publication number: 20240018147
    Abstract: Provided are a salt of a compound for degrading BTK, and/or a crystal form, preparation therefor, and an application thereof.
    Type: Application
    Filed: September 8, 2021
    Publication date: January 18, 2024
    Applicant: HAISCO PHARMACEUTICALS PTE. LTD.
    Inventors: Chen Zhang, Yuting Liao, Jianmin Wang, Longbin Huang, Guozhi Zhu, Yao Li, Pangke Yan
  • Nitrile derivative that acts as inhibitor of dipeptidyl peptidase 1 and use thereof
    Patent number: 11807635
    Abstract: Disclosed is a nitrile derivative compound represented by formula (I), a stereoisomer, a deuterated product, a co-crystal, a solvate or a pharmaceutically acceptable salt thereof, wherein each group is as defined in the description. The compound has dipeptidyl peptidase 1 inhibitory activity and can be used to prepare a drug for treating diseases including obstructive airway diseases, bronchiectasis, cystic fibrosis, asthma, emphysema, and chronic obstructive pulmonary diseases.
    Type: Grant
    Filed: October 28, 2022
    Date of Patent: November 7, 2023
    Assignee: Haisco Pharmaceuticals Pte. Ltd.
    Inventors: Yao Li, Zongjun Shi, Guobiao Zhang, Lei Chen, Wenjing Wang, Xiaobo Zhang, Dengyu Zheng, Bo Xu, Xin Liu, Yajun Wang, Fei Ye, Pingming Tang, Jia Ni, Chen Zhang, Pangke Yan
  • NITRILE DERIVATIVE THAT ACTS AS INHIBITOR OF DIPEPTIDYL PEPTIDASE 1 AND USE THEREOF
    Publication number: 20230121807
    Abstract: Disclosed is a nitrile derivative compound represented by formula (I), a stereoisomer, a deuterated product, a co-crystal, a solvate or a pharmaceutically acceptable salt thereof, wherein each group is as defined in the description. The compound has dipeptidyl peptidase 1 inhibitory activity and can be used to prepare a drug for treating diseases including obstructive airway diseases, bronchiectasis, cystic fibrosis, asthma, emphysema, and chronic obstructive pulmonary diseases.
    Type: Application
    Filed: October 28, 2022
    Publication date: April 20, 2023
    Applicant: HAISCO PHARMACEUTICALS PTE. LTD
    Inventors: Yao Li, Zongjun Shi, Guobiao ZHANG, Lei Chen, Wenjing Wang, Xiaobo Zhang, Dengyu Zheng, Bo Xu, Xin Liu, Yajun Wang, Fei Ye, Pingming Tang, Jia Ni, Chen Zhang, Pangke Yan
  • Substituted piperidines as BTK inhibitors
    Patent number: 11542266
    Abstract: Substituted piperidines as BTK inhibitors, a preparation method thereof and a pharmaceutical application thereof. The substituted piperidines is a compound represented by a general formula (I) or a stereoisomer or a pharmaceutically acceptable salt thereof, and the substituted piperidines is used to treat BTK-related diseases such as tumors or autoimmune system diseases.
    Type: Grant
    Filed: October 6, 2021
    Date of Patent: January 3, 2023
    Assignee: HAISCO PHARMACEUTICALS PTE. LTD.
    Inventors: Chen Zhang, Yuting Liao, Jianmin Wang, Guozhi Zhu, Fei Ye, Pingming Tang, Xiaogang Chen, Zhenggang Huang, Shoutao Wu, Yao Li, Pangke Yan