Patents Assigned to Hamamatsu Foundation for Science and Technology Promotion
  • Patent number: 8080378
    Abstract: A method for detecting colon cancer by detecting COX-2 from a human feces sample or detecting COX-2 RNA from a human feces sample.
    Type: Grant
    Filed: July 14, 2009
    Date of Patent: December 20, 2011
    Assignees: Hamamatsu Foundation for Science and Technology Promotion, Olympus Corporation
    Inventor: Shigeru Kanaoka
  • Publication number: 20110193553
    Abstract: A magnetic array sensor circuit to process an output from a magnetic sensor array including a plurality of magnetic sensor elements arranged in an array. The circuit includes a regulating circuit to reduce an offset variation of the output from the magnetic sensor elements arranged in the array.
    Type: Application
    Filed: April 13, 2011
    Publication date: August 11, 2011
    Applicants: NTN Corporation, Hamamatsu Foundation for Science and Technology Promotion
    Inventors: Toru Takahashi, Shoji Kawahito
  • Patent number: 7948231
    Abstract: A rotation detecting apparatus capable of increasing the angle detecting precision without being affected by an offset signal resulting from a stress in a silicon chip. The rotation detecting apparatus includes a magnetic sensor array and a magnet rotatable in face-to-face relation with the magnetic sensor array. The magnetic sensor array includes a plurality of groups of sensor elements, each group including four sensor elements. The four sensor elements of each combined sensor element group are so arranged as to be oriented vertically and horizontally in four directions and connected parallel to each other.
    Type: Grant
    Filed: December 6, 2005
    Date of Patent: May 24, 2011
    Assignees: NTN Corporation, Hamamatsu Foundation for Science and Technology Promotion
    Inventors: Toru Takahashi, Shoji Kawahito
  • Publication number: 20110081033
    Abstract: An audio transducing processor can be adjusted under conditions based on the subjectivity of an actual wearer and can improve the wearer's comfort. A method for adjusting an audio transducing processor provided with a cochlear implant for augmenting audition by giving audio information as stimulus pulses to a cochlea of a wearer can comprise an audiometry step for finding an audible sound range of the wearer using frequency and sound pressure as variables, and adjusting the audio transducing processor on the basis of hearing acuity data obtained from the audiometry step.
    Type: Application
    Filed: September 7, 2010
    Publication date: April 7, 2011
    Applicant: HAMAMATSU FOUNDATION FOR SCIENCE AND TECHNOLOGY PROMOTION
    Inventor: Shigeyoshi Kitazawa
  • Publication number: 20100323367
    Abstract: It is intended to provide a non-invasive and convenient method of detecting a tumor marker for diagnosing colon cancer which is superior in sensitivity and specificity to the existing fecal occult blood test. More specifically speaking, a method of detecting a tumor marker for diagnosing colon cancer which comprises collecting biological sample which is immediately frozen using liquid nitrogen in some cases, homogenizing the sample in the presence of an inhibitor of an RNA digesting enzyme to give a suspension, extracting RNA from the obtained suspension, subjecting the extracted RNA to reverse transcription to give cDNA. amplifying the obtained cDNA and then detecting the thus amplified cDNA. This method is characterized by involving no procedure of separating cell components from the biological sample.
    Type: Application
    Filed: September 3, 2010
    Publication date: December 23, 2010
    Applicants: OLYMPUS CORPORATION, HAMAMATSU FOUNDATION FOR SCIENCE AND TECHNOLOGY PROMOTION
    Inventor: Shigeru Kanaoka
  • Patent number: 7816077
    Abstract: It is intended to provide a non-invasive and convenient method of detecting a tumor marker for diagnosing colon cancer which is superior in sensitivity and specificity to the existing fecal occult blood test. More specifically speaking, a method of detecting a tumor marker for diagnosing colon cancer which comprises collecting biological sample which is immediately frozen using liquid nitrogen in some cases, homogenizing the sample in the presence of an inhibitor of an RNA digesting enzyme to give a suspension, extracting RNA from the obtained suspension, subjecting the extracted RNA to reverse transcription to give cDNA, amplifying the obtained cDNA and then detecting the thus amplified cDNA. This method is characterized by involving no procedure of separating cell components from the biological sample.
    Type: Grant
    Filed: September 19, 2003
    Date of Patent: October 19, 2010
    Assignees: Hamamatsu Foundation for Science and Technology Promotion, Olympus Corporation
    Inventor: Shigeru Kanaoka
  • Publication number: 20100158189
    Abstract: A Mossbauer spectrometer 1A uses a configuration including: a stage 10 for holding a sample S; a ?-ray irradiating unit 15 for supplying measurement ? rays; ?-ray converging unit 18 for irradiating the sample S with the measurement ? rays in a converging manner; an electron detector 20, having an opening through which the measurement ? rays are passed and being configured so that a surface on a side of the stage 10 is used as an electron incident surface, for detecting internal conversion electrons from the target substance in the sample S in which the measurement ? rays are absorbed in resonance; an irradiation position moving unit for two-dimensionally moving an irradiation position of the measurement ? rays with respect to the sample S within an XY plane; and an energy selecting voltage applying unit for selecting energy of the electrons detected by the electron detector 20 by applying voltage to the electron incident surface of the electron detector 20 so that a potential of the electron incident surface
    Type: Application
    Filed: May 14, 2008
    Publication date: June 24, 2010
    Applicant: HAMAMATSU FOUNDATION FOR SCIENCE AND TECHNOLOGY PROMOTION
    Inventor: Yutaka Yoshida
  • Patent number: 7627379
    Abstract: A method for speech conversion in an artificial auris interna and an artificial auris interna can be capable of providing speech near to natural speech to a person using the artificial auris interna and reproducing natural fluctuation at random with a value near to the periodicity unique to each channel. Within a signal frame, speech information can be distinguished according to each frequency band by using band pass filters. Channel information on the corresponding frequency band can be added to the speech information. For each channel, speech information having a large signal level within one channel is left so that the number of stimulus pulses can be adjusted to be a frequency allowed for one channel. From all the speech information left for each channel, the speech information having a large signal level is left so that the number of stimulus pulses is adjusted to be a frequency allowed for the entire channel.
    Type: Grant
    Filed: February 7, 2006
    Date of Patent: December 1, 2009
    Assignee: Hamamatsu Foundation for Science and Technology Promotion
    Inventors: Shigeyoshi Kitazawa, Shinya Kiriyama, Erdenebat Dashtseren, Satoshi Iwasaki
  • Publication number: 20090291447
    Abstract: It is intended to provide a non-invasive and convenient method of detecting a tumor marker for diagnosing colon cancer which is superior in sensitivity and specificity to the existing fecal occult blood test. More specifically speaking, a method of detecting a tumor marker for diagnosing colon cancer which comprises collecting biological sample which is immediately frozen using liquid nitrogen in some cases, homogenizing the sample in the presence of an inhibitor of an RNA digesting enzyme to give a suspension, extracting RNA from the obtained suspension, subjecting the extracted RNA to reverse transcription to give cDNA, amplifying the obtained cDNA and then detecting the thus amplified cDNA. This method is characterized by involving no procedure of separating cell components from the biological sample.
    Type: Application
    Filed: July 14, 2009
    Publication date: November 26, 2009
    Applicant: HAMAMATSU FOUNDATION FOR SCIENCE AND TECHNOLOGY PROMOTION
    Inventor: Shigeru Kanaoka
  • Publication number: 20090148840
    Abstract: A method of detecting a tumor marker for the diagnosis of large bowel cancer and adenomatous polyposis coli comprising the steps of a) collecting and freezing feces, b) homogenizing the frozen feces in the presence of an RNAase inhibitor and preparing a suspension, c) extracting RNA from the obtained sample from which RNA is extracted, d) obtaining cDNA by reverse transcribing the extracted RNA, e) amplifying the obtained cDNA, and f) detecting the amplified cDNA, characterized in that the tumor marker is one or more tumor markers selected from the group consisting of COX-2, SNAIL and MMP-7 (with the proviso that a case where only COX-2 or MMP-7 is selected is excluded).
    Type: Application
    Filed: August 10, 2006
    Publication date: June 11, 2009
    Applicant: Hamamatsu Foundation for Science and Technology Promotion
    Inventor: Shigeru Kanaoka
  • Publication number: 20090126226
    Abstract: An inner sole for an insole has a body made of flexible material and adapted to be laid on an insole of a shoe. Liquid containing spaces are formed in the body of the inner sole for sealingly and flowably containing liquid. Dam portions divide the liquid containing spaces into a toe region, a heel region and a middle region between the two. Orifices communicate the liquid between mutually adjacent regions. The orifice formed by the dam portions that divides the liquid containing spaces into the heel region and the middle region opens toward one side edge portion to cause an eddy of liquid, flowing from the heel region into the middle region, that substantially fills the whole middle region.
    Type: Application
    Filed: November 14, 2008
    Publication date: May 21, 2009
    Applicants: Hamamatsu Foundation for Science and Technology Promotion, Walking Day Co., Ltd.
    Inventors: Nobuyoshi Morita, Junichi Takano
  • Patent number: 7483609
    Abstract: An image wavelength conversion device for converting an infrared light image into a visible light, a method of manufacturing the device, and an image conversion system using the device are provided. The image wavelength conversion device is formed by an optical waveguide array 3 in which one end and the other end of each of a multitude of quasi-phase-matching sum frequency generating optical waveguides are aligned in a two-dimensional plane. One plane of the optical waveguide array 3 forms an incident plane which includes respective waveguides as elements thereof, and the other plane of the optical waveguide array 3 forms an exit plane which includes waveguides corresponding to the waveguides of the incident plane as elements thereof. From an incident light (?1) and an excitation light (?2) incident to an arbitrary element of the incident plane, an output light (?3) having the relationship of (?1)?1+(?2)?1=(?3)?1 is generated in the corresponding waveguide element.
    Type: Grant
    Filed: March 15, 2005
    Date of Patent: January 27, 2009
    Assignee: Hamamatsu Foundation for Science and Technology Promotion
    Inventor: Makoto Minakata
  • Publication number: 20080292860
    Abstract: An ultrasonic vibration cutting method for drilling a workpiece using a drill applied to the workpiece. Ultrasonic torsional mode vibration in its rotational direction is applied to the drill. The workpiece is a fiber reinforced plastic member including carbon fibers as its reinforcing fibers. The drilling by the drill, with the ultrasonic torsional mode vibration in its rotational direction, provides a drilled surface that is substantially smooth.
    Type: Application
    Filed: May 23, 2008
    Publication date: November 27, 2008
    Applicant: Hamamatsu Foundation for Science and Technology Promotion
    Inventor: Hukuzo Yagishita
  • Publication number: 20080028638
    Abstract: An inner sole to be laid on an insole of a shoe can have a body made of flexible material and formed therein with a liquid containing space for sealingly and flowably containing liquid therein. The inner sole can include dam portions for dividing the liquid containing space into a toe region, a heel region and a middle region therebetween, and orifices for communicating the liquid between mutually adjacent regions at a predetermined flowing rate.
    Type: Application
    Filed: April 6, 2007
    Publication date: February 7, 2008
    Applicants: Hamamatsu Foundation for Science and Technology Promotion
    Inventors: Nobuyoshi Morita, Junichi Takano
  • Publication number: 20070284529
    Abstract: An image wavelength conversion device for converting an infrared light image into a visible light, a method of manufacturing the device, and an image conversion system using the device are provided. The image wavelength conversion device is formed by an optical waveguide array 3 in which one end and the other end of each of a multitude of quasi-phase-matching sum frequency generating optical waveguides are aligned in a two-dimensional plane. One plane of the optical waveguide array 3 forms an incident plane which includes respective waveguides as elements thereof, and the other plane of the optical waveguide array 3 forms an exit plane which includes waveguides corresponding to the waveguides of the incident plane as elements thereof. From an incident light (?1) and an excitation light (?2) incident to an arbitrary element of the incident plane, an output light (?3) having the relationship of (?1)?1+(?2)?1=(?3)?1 is generated in the corresponding waveguide element.
    Type: Application
    Filed: March 15, 2005
    Publication date: December 13, 2007
    Applicant: Hamamatsu Foundation For Science And Technology Promotion
    Inventor: Makoto Minakata