Abstract: The present invention provides for a mobile and self-contained sanitizing wipe dispensing system that dispenses discreet sheets of sanitizing wipes for hand or surface sanitization. The system is configured to facilitate the consistent dispensing of individual wipes, preferably from a roll of perforated but attached wipes, such that each wipe is separated at the point of perforation and the leading edge of the following sheet for easy access of each successive wipe. Means are provided to dispense wipes from a wall that is incorporated into the system, a plurality of walls forming an enclosure. The enclosure functions as a storage device for its own wipe refills and provides an integrated receptacle for used wipes. One embodiment comprises walls that are like-configured for ease in production and assembly and for reducing the cost of production.