Patents Assigned to HANGZHOU CITY UNIVERSITY
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Publication number: 20250134905Abstract: The present invention relates to use of homoharringtonine in manufacturing a drug for treating an acquired immunodeficiency syndrome. A homoharringtonine compound is prepared as a drug for treating the acquired immunodeficiency syndrome and is applied to the treatment of the acquired immunodeficiency syndrome. The homoharringtonine compound can significantly reduce the programmed ribosomal frameshifting (PRF) efficiency of the mRNA of HIV-1 during the translation of a Gag-Pol fusion protein to substantially decrease the translation efficiency of the Pol protein. Therefore, the cell fails to produce protease, integrase, and reverse transcriptase obtained via Pol splicing such that a virus cannot be packaged effectively, which eventually leads to a sharp decline in yield of the virus. Therefore, the compound of the present invention has a good anti-HIV effect.Type: ApplicationFiled: October 16, 2024Publication date: May 1, 2025Applicant: Hangzhou City UniversityInventors: Geng YANG, Yashuang JIANG, Zhujiao ZHOU, Chong ZHANG, Jingyi YANG, Xiaolei PAN, Jiankang ZHANG, Jiajia WANG
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Patent number: 12230481Abstract: A plasma reactor, configured to process low temperature plasma, includes: a rotating reactor, a fixed reactor, and a master tube. An end of the master tube is connected to two branched tubes, one of the two branched tubes is connected to the rotating reactor, and the other one of the two branched tubes is connected to the fixed reactor. When a flow rate of inlet gas is less than a threshold defined by a flow detector, all the gas enters the rotating reactor from one of the two branched tubes. When the flow rate of the inlet gas is greater than the threshold of the flow detector, a valve is configured to operate to allow a part of the inlet gas that exceeds the threshold to enter the fixed reactor from the other one of the two branched tubes.Type: GrantFiled: February 13, 2023Date of Patent: February 18, 2025Assignee: HANGZHOU CITY UNIVERSITYInventors: Qi Qiu, Pengfei Wang, Jiahong Fu, Xingliang Liu, Zhaozhe Deng
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Patent number: 12078489Abstract: The invention relates to a weight and reference quaternion correction unscented quaternion estimation method, comprising: obtaining measurement data as quantity measurement through a gyro and a star sensor; establishing a quaternion-based discrete spacecraft nonlinear state space model; estimating an error quaternion, a gyro drift and a corresponding error covariance at a k moment by using an unscented quaternion estimator based on parameter and reference quaternion correction at a k?1 moment; and setting a filtering time as Ntime, if k<Ntime, then repeating the step 3, if k=Ntime, then finishing filtering, and outputting the attitude quaternion, the gyro drift and the corresponding error covariance.Type: GrantFiled: January 29, 2024Date of Patent: September 3, 2024Assignee: Hangzhou City UniversityInventors: Zhenbing Qiu, Yanjun Li
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Patent number: 12037763Abstract: An auger-suction type metro jet system (MJS) device for aerated and lightweight cement soil includes a multi-pipe device, an outer sleeve, an integrated device, a spiral conveyor, a reamer head, a pressure monitoring system, a mass measuring device, and a control console. The multi-pipe device integrates a backup pipe, a negative-pressure gas pipe, a hydraulic pipe, a negative-pressure water pipe, a pressure sensor wire pipe, a pressure water pipe, a backup gas pipe, a power wire pipe, and at least one grouting tremie unit. The spiral conveyor includes a shaft-type spiral conveying belt and a negative-pressure device. A construction method for foundation reinforcement construction includes: cutting soil by the reamer head; crushing gravel by a gravel crusher; transporting, by the shaft-type spiral conveying belt, a soil-water mixture to a waste liquid tank; monitoring, by the mass measuring device, a mass of the soil-water mixture discharged; and injecting equal-mass cement.Type: GrantFiled: December 29, 2023Date of Patent: July 16, 2024Assignee: HANGZHOU CITY UNIVERSITYInventors: Lisha Zhang, Xiao Wei, Zhongxuan Yang, Yunliang Cui, Xinquan Wang, Fushen Liu, Chaofa Zhao
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Patent number: 12031637Abstract: A two-dimensional electro-hydraulic servo valve based on a dual-redundancy transmission mechanism, including a valve body, a valve spool inside the valve body, and a valve sleeve on an outside of the valve spool. A low-pressure chamber is disposed between the valve spool and the valve sleeve; the valve body is connected to a servomotor through a transmission mechanism; the transmission mechanism includes a spool fork and a motor toggle, and each end of the motor toggle is connected to a spherical connector; the spherical connector is rotatable with a centerline of a connection end of the motor toggle as an axis; each end of the spool fork is slidably connected to a corresponding spherical connector; a middle part of the spool fork is connected to the valve spool, and a middle part of the motor toggle is connected to a rotor of the servomotor.Type: GrantFiled: December 14, 2023Date of Patent: July 9, 2024Assignees: HANGZHOU CITY UNIVERSITY, ZHEJIANG UNIVERSITYInventors: Qilin Jin, Qiang Zuo, Qianqian Lu, Yu Huang, Longlong Leng, Jiaqi Hu, Yongzhuang Liu, Binbin Chen
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Patent number: 12017809Abstract: The present disclosure provides a device for detecting carbon emission of a passive house. The device for detecting carbon emission of a passive house is arranged on a metal rain cap at a top of a chimney. The device for detecting carbon emission of a passive house includes an unmanned aerial vehicle, a guide assembly, and two landing gear assemblies. The two landing gear assemblies are arranged at a bottom of the unmanned aerial vehicle, the guide assembly is arranged at a bottom of the two landing gear assemblies, and the guide assembly includes two split assemblies. The two split assemblies correspond one-to-one to the two landing gear assemblies, and the split assemblies are in linked connection to the landing gear assemblies. In the device for detecting carbon emission of a passive house, the unmanned aerial vehicle, the guide assembly and the two landing gear assemblies are arranged to cooperate with each other.Type: GrantFiled: October 25, 2022Date of Patent: June 25, 2024Assignee: Hangzhou City UniversityInventors: Haijun Bao, Ning Wang
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Publication number: 20240181707Abstract: A method for optimizing design and manufacture of a self-supporting structure based on multi-axis 3D printing are provided, which comprises the following steps: using a structural topology optimization method based on an SIMP model to achieve the optimal configuration design of a complex structure, converting an image into a binary image, and post-processing the result of topology optimization; determining an overhanging angle of a structure boundary, and determining the printing direction of different printing partitions according to the classification; performing integrated optimization of angle constraints; extracting structural information, establishing a 3D solid model, and then partitioning and slicing the model, and generating a printing path for self-supporting multi-axis 3D printing manufacturing. The present disclosure has the beneficial effects that the self-supporting structure is generated in the optimization process, no additional support is needed in the printing process.Type: ApplicationFiled: September 5, 2023Publication date: June 6, 2024Applicants: HANGZHOU CITY UNIVERSITY, ZHEJIANG UNIVERSITYInventors: Zhen WANG, Jun YE, Yang ZHAO, Hongjia LU, Qichen GUO, Huiping TANG, Guan QUAN, Zhi DING
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Patent number: 11988093Abstract: An inflatable folding tunnel reinforcement structure and a construction method thereof are provided. The inflatable folding tunnel reinforcement structure includes an inflation port, an airbag, a water blocking net, a steel plate, a scissor folding mechanism, a vertical support plate, an arc-shaped support plate, drainage channels, an upper support rod, a lower support rod, a locking pin, a threaded steel rod, a rolling connection pin, and an induction motor, where the upper support rod and the lower support rod are unfolded in opposite directions to a preset position through the steel rod; and the drainage channels are configured to perform water guidance and resistance for a leakage-proofing purpose. The construction method includes: preparation before construction, device fixation, on-site construction, structural inspection, and site cleaning.Type: GrantFiled: January 4, 2023Date of Patent: May 21, 2024Assignee: Hangzhou City UniversityInventors: Gang Wei, Tianbao Xu, Xin Li, Tianyu Zhu, Shuangyan Lin, Luju Liang, Chengbao Hu, Xiao Wang
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Patent number: 11968769Abstract: A dielectric barrier discharging tube, which has a synergistic column of needle electrodes to utilize a plurality of channels to adsorb catalysts, is provided. The dielectric barrier discharging tube includes: a quartz tube, a high-voltage pole, an inner electrode, and a plurality discharging needle sets. Two catalytic blocks are arranged respectively on two sides of each set discharging needles. Each catalytic block defines at least one inclined inner channel and at least one inclined outer channel. A higher end of each channel faces towards the discharging needle, and a lower end of each channel faces towards the discharging needle.Type: GrantFiled: December 21, 2023Date of Patent: April 23, 2024Assignee: HANGZHOU CITY UNIVERSITYInventors: Qi Qiu, Pengfei Wang, Qinmin Yang, Hao Chen
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Patent number: 11958620Abstract: The present disclosure relates to a hydrogen electric hybrid power plant for a hovercar. The hydrogen electric hybrid power plant comprises a first-stage duct, a transition duct and a second-stage duct. An air outlet end of the first-stage duct is connected to the second-stage duct through the transition duct. A hydrogen reactor is arranged in the first-stage duct, and the hydrogen reactor is fixed with the first-stage duct through a plurality of supporting pieces A. A primary filter screen is arranged at a front end of the first-stage duct and fixed on the first-stage duct through a hoop, so that low-altitude sundries and dust are prevented from entering the reactor. A return pipe is arranged, and the problems of oxygen supply, heat dissipation and cooling and the like of the hydrogen reactor are solved through ducted airflow. A motor power supply requirement of a ducted fan is met.Type: GrantFiled: May 16, 2023Date of Patent: April 16, 2024Assignee: HANGZHOU CITY UNIVERSITYInventor: Xinfeng Zhang
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Patent number: 11952728Abstract: A road structure reconstructed from large-scale independent underground garage and a construction method, which solves the problem of a newly constructed urban expressway passing through large underground space. The technical point is a construction method for the road structure reconstructed from large-scale independent underground garage, including the following steps: S100: segmentation for the garage, S200: preparation before construction: the materials and equipment required for construction are transported to the site, and the construction site is cleaned, S300: reconstruction for the front section, S400: reconstruction for the middle section, S500: reconstruction for the rear section. The inventiveness of the present disclosure is the application of segmentation construction, the front section is completely obsoleted, a transition section is provided at the middle, and the design of the rear section adopts a double-deck road, thus the original underground garage structure is fully utilized.Type: GrantFiled: July 12, 2023Date of Patent: April 9, 2024Assignee: HANGZHOU CITY UNIVERSITYInventors: Gang Wei, Tianbao Xu, Jiaxuan Zhu, Yunliang Cui, Bing Li, Ke Wang, Pengfei Xiang, Shuangyan Lin, Xinquan Wang, Hongguo Diao
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Publication number: 20240076984Abstract: An inflatable folding tunnel reinforcement structure and a construction method thereof are provided. The inflatable folding tunnel reinforcement structure includes an inflation port, an airbag, a water blocking net, a steel plate, a scissor folding mechanism, a vertical support plate, an arc-shaped support plate, drainage channels, an upper support rod, a lower support rod, a locking pin, a threaded steel rod, a rolling connection pin, and an induction motor, where the upper support rod and the lower support rod are unfolded in opposite directions to a preset position through the steel rod; and the drainage channels are configured to perform water guidance and resistance for a leakage-proofing purpose. The construction method includes: preparation before construction, device fixation, on-site construction, structural inspection, and site cleaning. The present disclosure can treat various tunnel defects efficiently and conveniently and achieve a desired leakage-proofing effect.Type: ApplicationFiled: January 4, 2023Publication date: March 7, 2024Applicant: Hangzhou City UniversityInventors: Gang WEI, Tianbao XU, Xin LI, Tianyu ZHU, Shuangyan LIN, Luju LIANG, Chengbao HU, Xiao WANG
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Patent number: 11891997Abstract: The present disclosure provides a two-dimensional motor piston pump, including a two-dimensional motor and a two-dimensional piston pump. The two-dimensional motor and the two-dimensional piston pump are nested with each other and arranged coaxially. The two-dimensional motor includes a stator and an outer rotor, and the outer rotor is coaxial with the stator and is sleeved outside the stator. The two-dimensional piston pump includes: a flow distribution mechanism including a flow distribution rotor and a pump body, a piston mechanism including a left cam and a right cam; a roller assembly including a roller and a roller shaft, and a pump housing, a left end cover, and a right end cover.Type: GrantFiled: May 9, 2023Date of Patent: February 6, 2024Assignees: ZHEJIANG UNIVERSITY, HANGZHOU CITY UNIVERSITY, WENZHOU UNIVERSITYInventors: Qiang Zuo, Longlong Leng, Qilin Jin, Yan Ren, Zhuhua Deng, Wei Shao, Quankun Li, Pengfei Wang, Zheng Wang, Liying Lou, Yanwei Zhao
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Patent number: 11895764Abstract: A dielectric barrier discharge tube includes a quartz tube, the middle of the quartz tube is sleeved with a high-voltage electrode, an inner electrode is arranged in the quartz tube, a drive fan is arranged at the end of the inner electrode, a discharging needle set is arranged on the surface of the inner electrode, and a spiral discharging wire is suspended and arranged at the tip of the discharging needle set. After a high voltage electric field is applied to the high voltage electrode, the discharging needle set and the spiral discharging wire discharge, the discharging needle set and the spiral discharging wire discharge at different time points. When the gas passes through the driving fan, the flow direction of the gas is changed. A cyclone can be generated to drive the gas to flow towards the discharging area.Type: GrantFiled: July 2, 2023Date of Patent: February 6, 2024Assignee: HANGZHOU CITY UNIVERSITYInventors: Qi Qiu, Pengfei Wang, Qinmin Yang
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Patent number: 11885318Abstract: A two-dimensional motor combination piston pump by combining two independent two-dimensional piston pumps into one structure is provided. The combination piston pump includes a two-dimensional motor and a two-dimensional piston pump. The outer rotator serves as the piston and the flow distribution mechanism of the two-dimensional piston pump. While operating, outer rotator rotates and moves axially.Type: GrantFiled: May 10, 2023Date of Patent: January 30, 2024Assignees: HANGZHOU CITY UNIVERSITY, ZHEJIANG UNIVERSITY, WENZHOU UNIVERSITYInventors: Longlong Leng, Qiang Zuo, Qilin Jin, Yan Ren, Zhuhua Deng, Wei Shao, Quankun Li, Pengfei Wang, Zheng Wang, Liying Lou, Yanwei Zhao
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Publication number: 20240010347Abstract: The present disclosure relates to a hydrogen electric hybrid power plant for a hovercar. The hydrogen electric hybrid power plant comprises a first-stage duct, a transition duct and a second-stage duct. An air outlet end of the first-stage duct is connected to the second-stage duct through the transition duct. A hydrogen reactor is arranged in the first-stage duct, and the hydrogen reactor is fixed with the first-stage duct through a plurality of supporting pieces A. A primary filter screen is arranged at a front end of the first-stage duct and fixed on the first-stage duct through a hoop, so that low-altitude sundries and dust are prevented from entering the reactor. A return pipe is arranged, and the problems of oxygen supply, heat dissipation and cooling and the like of the hydrogen reactor are solved through ducted airflow. A motor power supply requirement of a ducted fan is met.Type: ApplicationFiled: May 16, 2023Publication date: January 11, 2024Applicant: HANGZHOU CITY UNIVERSITYInventor: Xinfeng Zhang
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Patent number: 11795075Abstract: A vacuum-flocculation-solidification integrated apparatus for waste mud and a using method thereof are provided, and the apparatus includes an outer support truss, a vacuum barrel wall, a flocculation stirring device, and a rotary spraying solidification device. The using method of the apparatus includes: flattening a site and installing a support truss and a vacuum barrel wall; assembling a flocculation stirring device and then hoisting and installing to a top of the vacuum barrel wall; checking an air tightness; adding an APAM flocculant, starting the flocculation stirring device and a vacuum pump; starting an air compressor; and squeezing solidified soil from soil outlets. Beneficial effects of apparatus are that: multiple procedures of flocculation, vacuum drainage, solidification and discharging soil for the waste mud are continuously performed; a solidification agent is fully mixed with solidified soil through rotary spraying; and the apparatus is convenient to be disassembled, reassembled, and reused.Type: GrantFiled: June 17, 2023Date of Patent: October 24, 2023Assignee: HANGZHOU CITY UNIVERSITYInventors: Yunliang Cui, Qunchao Ma, Zhipeng Liu, Huiming Li, Chao Chen, Kai Xu, Junshuai Zhang
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Patent number: 11786863Abstract: A low-temperature plasma reactor having an adaptive rotating electrode includes a frame. A reaction tube is arranged inside the frame. A fixing cover is arranged on each of two sides of the frame. The fixing cover defines a through hole communicating with an inside of the reaction tube. The through hole in one of the two sides serves as an air inlet hole, and the through hole in the other one of the two sides serves as an air outlet hole. A rotatable inner electrode is arranged inside the reaction tube, a plurality of groups of discharging needles are arranged on a surface of the inner electrode. A rotating fan is arranged on the inner electrode and is disposed on a side of the air inlet hole. The gas flow drives the inner electrode and the discharging needles to rotate, and a motor drive is not required.Type: GrantFiled: February 13, 2023Date of Patent: October 17, 2023Assignee: HANGZHOU CITY UNIVERSITYInventors: Qi Qiu, Pengfei Wang, Jiahong Fu, Xingliang Liu, Zhaozhe Deng
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Patent number: 11733128Abstract: A test device and method for studying influence of external load on soil arching effect of shield tunnel, including a test chamber, a tunnel model and a control module. The tunnel model, including segments which are meshed with each other and can move relatively, the tunnel model is installed in the middle of the test chamber, and all sides of the tunnel model is filled with a test soil, the control module, including a set of deceleration motors and a variable cross-section guide rod, the variable cross-section guide rod is inserted into the tunnel model, which can reduce the diameter of the tunnel model, resulting in ground loss and soil arching effect.Type: GrantFiled: February 15, 2023Date of Patent: August 22, 2023Assignee: HANGZHOU CITY UNIVERSITYInventors: Luju Liang, Zhi Ding, Gang Wei, Changjie Xu
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Patent number: 11703067Abstract: An electro-hydraulic servo valve, which has an adjustable null position and can be directly driven by the motor, is provided and includes four parts: a slide valve assembly, a two-dimensional motor, a magnet resetting-to-null mechanism, and a displacement sensor, and the four parts are set coaxially arranged. The slide valve assembly is a conventional two-dimensional servo valve structure. The two-dimensional motor may directly drive the valve core to rotate to further control a size of an opening opened by a valve. The magnet resetting-to-null mechanism is configured to reset the valve to the null position. The displacement sensor may monitor a position of the valve core in real-time and feedback signals to achieve closed-loop controlling.Type: GrantFiled: September 30, 2022Date of Patent: July 18, 2023Assignees: HANGZHOU CITY UNIVERSITY, SHANGHAI MARINE EQUIPMENT RESEARCH INSTITUTEInventors: Qiang Zuo, Xian Zhang, Yaolan Jin, Zhuhua Deng, Wei Shao, Pengfei Wang, Jie Xiong, Liying Lou, Yanwei Zhao, Longlong Leng