Abstract: The present invention relates to a cyclic peptide compound, and a preparation method, pharmaceutical composition and use thereof. In particular, the cyclic peptide compound of the present invention has a structure as shown by general formula (I). The compound of general formula (I), and isomers, racemates, pharmaceutically acceptable salts, crystalline hydrates, solvates or mixtures thereof have a use in the preparation of medicaments for preventing or treating mammalian diseases associated with histone deacetylase dysregulations.
Type:
Grant
Filed:
September 2, 2014
Date of Patent:
September 4, 2018
Assignee:
HANGZHOU GUANYU BIO-MEDICAL CO., LTD.
Inventors:
Sheng Jiang, Zhiyi Yao, Yiwu Yao, Yatao Qiu, Changyin Lu, Kun Su, Xiaoming Yao
Abstract: The present invention relates to a cyclic peptide compound, and a preparation method, pharmaceutical composition and use thereof. In particular, the cyclic peptide compound of the present invention has a structure as shown by general formula (I). The compound of general formula (I), and isomers, racemates, pharmaceutically acceptable salts, crystalline hydrates, solvates or mixtures thereof have a use in the preparation of medicaments for preventing or treating mammalian diseases associated with histone deacetylase dysregulations.
Type:
Application
Filed:
September 2, 2014
Publication date:
September 29, 2016
Applicant:
HANGZHOU GUANYU BIO-MEDICAL CO., LTD.
Inventors:
Sheng Jiang, Zhiyi Yao, Yiwu Yao, Yatao Qiu, Changyin Lu, Kun Su, Xiaoming Yao