Patents Assigned to HANGZHOU HUADONG MEDICINE GROUP BIOPHARMACEUTICAL CO. LTD.
  • Pyrrolopyrimidine five-membered azacyclic derivative and application thereof
    Patent number: 10822339
    Abstract: The present invention relates to a pyrrolopyrimidine five-membered azacyclic derivative as a novel JAK kinase inhibitor, and use thereof in a preparation of a pharmaceutical product for preventing and/or treating an indication related to a JAK kinase function. The pyrrolopyrimidine five-membered azacyclic derivative of the invention is an ideal JAK kinase inhibitor with a high potency, and can be used to treat or prevent diseases such as rheumatoid arthritis, polycythemia vera, psoriasis, primary thrombocytosis, myelofibrosis, and the like.
    Type: Grant
    Filed: January 25, 2017
    Date of Patent: November 3, 2020
    Assignees: HANGZHOU HUADONG MEDICINE GROUP BIOPHARMACEUTICAL CO. LTD
    Inventors: Jianming Yin, Yubin Lv, Bangliang Li
  • Quinazolin crotyl compound dimaleate crystals and preparation methods and uses thereof
    Patent number: 10640470
    Abstract: Disclosed are crystal forms K, E, F and G of the dimaleate of the compound as shown in formula I, and preparation methods and uses thereof. The crystal forms K, E, F and G have superior storage stability and solubility, so that they are more suitable for being used as the drug substance for drug product preparations.
    Type: Grant
    Filed: June 25, 2018
    Date of Patent: May 5, 2020
    Assignee: HANGZHOU HUADONG MEDICINE GROUP BIOPHARMACEUTICAL CO. LTD.
    Inventors: Yubin Lv, Jianming Yin, Xuehui Huang, Bangliang Li
  • Quinazolin crotyl compound dimaleate crystals and preparation methods and uses thereof
    Patent number: 10065931
    Abstract: Disclosed are crystal forms K, E, F and G of the dimaleate of the compound as shown in formula I, and preparation methods and uses thereof. The crystal forms K, E, F and G have superior storage stability and solubility, so that they are more suitable for being used as the drug substance for drug product preparations.
    Type: Grant
    Filed: May 3, 2016
    Date of Patent: September 4, 2018
    Assignee: HANGZHOU HUADONG MEDICINE GROUP BIOPHARMACEUTICAL CO. LTD.
    Inventors: Yubin Lv, Jianming Yin, Xuehui Huang, Bangliang Li