Abstract: An apparatus for administering a cancer drug, comprising an optical emitter operatively arranged to emit a visible point of light onto a tissue surface to be treated, a robotic arm, operatively arrange to move a drug-delivery device, in sequence, to each of a plurality of predetermined positions within the tissue to be treated, a tactile sensor operatively arranged at the distal end of the drug-delivery device to determine vertical height movement of the robotic arm for contact of the tissue surface to be treated, a reservoir arranged to store the cancer drug, a needle, operatively arranged to be moved to each of the specific positions within the tissue, and to deliver the drug at those positions, and, a torch head for generating non-thermal plasma in proximity to an end of the needle and the area to be treated.

Abstract: A combination therapy for treating cancer including a DNA damaging agent deliverable to cancer cells and operatively arranged to activate only under a low oxygen condition and a non-thermal plasma deliverable to cancer cells. The non-thermal plasma and the DNA damaging agent individually and in conjunction promote cell toxicity.