Patents Assigned to Hanmi Holdings Co., Ltd.
  • Method for the mass production of immunoglobulin Fc region deleted initial methionine residues
    Patent number: 7968316
    Abstract: Disclosed is a method for the mass production of a monomeric or dimeric immunoglobulin Fc region, free of initial methionine residues, using a recombinant expression vector comprising a nucleotide sequence coding for a recombinant immunoglobulin Fc region comprising an immunoglobulin Fc region linked at the N-terminus thereof to an immunoglobulin Fc region via a peptide bond.
    Type: Grant
    Filed: August 16, 2006
    Date of Patent: June 28, 2011
    Assignee: Hanmi Holdings Co., Ltd.
    Inventors: Sung youb Jung, Jin Sun Kim, Jin hwan Shin, Se-Chang Kwon, Gwan-Sun Lee, Dae hae Song
  • STYRYLBENZOFURAN DERIVATIVES AS INHIBITORS FOR BETA-AMYLOID FIBRIL FORMATION AND PREPARATION METHOD THEREOF
    Publication number: 20110124888
    Abstract: The present invention relates to a novel compound which efficiently inhibits the formation of beta-amyloid fibrils in the brain to be useful for preventing or treating a degenerative brain disease, a method for preparing same, and a pharmaceutical composition comprising same as an active ingredient.
    Type: Application
    Filed: June 12, 2009
    Publication date: May 26, 2011
    Applicants: Korea Institute of Science and Technology, HANMI HOLDINGS CO., LTD
    Inventors: Dong Jin Kim, Kyung Ho Yoo, Ji Hun Byun, YoungSoo Kim, Hye Yun Kim, Gwan Sun Lee, Maeng Sup Kim, Young Gil Ahn, Ji Hoon Lee, Myoung-Hwan Lee, Hana Hwang, Jiyeon Ryu
  • METHOD FOR PREPARING HIGH-PURITY POLYETHYLENEGLYCOL ALDEHYDE DERIVATIVES
    Publication number: 20110071262
    Abstract: A method for preparing high-purity polyethyleneglycol-alkylenealdehydes and derivatives thereof is provided.
    Type: Application
    Filed: May 19, 2009
    Publication date: March 24, 2011
    Applicants: ID BIOCHEM, INC., HANMI HOLDINGS CO., LTD.
    Inventors: Pyeong-uk Park, Seong-Nyun Kim, Woo-Hyuk Choi, Hak-Sun Jang, Gwan-Sun Lee, Se-Chang Kwon
  • Method of preparing esomeprazole and salts thereof
    Patent number: 7888511
    Abstract: Optically pure esomeprazole and its salt can be simply prepared by dissolving (S)-(?)-binol, a weak base and the racemic form of omeprazole in a mixture of a water-compatible organic solvent and water at a high temperature, cooling the mixed solution to crystallize the inclusion complex of esomeprazole and (S)-(?)-binol, and removing the (S)-(?)-binol moiety from the crystallized inclusion complex.
    Type: Grant
    Filed: July 11, 2006
    Date of Patent: February 15, 2011
    Assignee: Hanmi Holdings Co., Ltd.
    Inventors: Tae Hee Ha, Won Jeong Kim, Hee Sook Oh, Chang Hee Park, Jae Chul Lee, Han Kyong Kim, Kwee-Hyun Suh