Patents Assigned to Hansa Medical Research AB
  • IdeS, an IgG-degrading enzyme of
    Patent number: 7666582
    Abstract: A polypeptide isolated from S. pyogenes is described, having IgG cysteine protease activity. The protease is designated IdeS, Immunoglobulin G-degrading enzyme of S. pyogenes. A polypeptide comprises SEQ ID NO: 1 and variants and fragments thereof having IgG cysteine protease activity or the ability to generate an immune response against S. pyogenes in an individual. Polynucleotides encoding these polypeptides and the polypeptides may be used in generating an immune response in an individual. IdeS protease inhibitors may be used in the treatment of S. pyogenes infection.
    Type: Grant
    Filed: December 17, 2002
    Date of Patent: February 23, 2010
    Assignee: Hansa Medical Research AB
    Inventors: Ulrich Von Pawel-Rammingen, Bjorn Johansson, Lars Björck
  • IdeS, an IgG-degrading enzyme of Streptococcus pyogenes
    Publication number: 20070237784
    Abstract: A polypeptide isolated from S. pyogenes is described, having IgG cysteine protease activity. The protease is designated IdeS, Immunoglobulin G-degrading enzyme of S. pyogenes. A polypeptide comprises SEQ ID NO: 1 and variants and fragments thereof having IgG cysteine protease activity or the ability to generate an immune response against S. pyogenes in an individual. Polynucleotides encoding these polypeptides and the polypeptides may be used in generating an immune response in an individual. IdeS protease inhibitors may be used in the treatment of S. pyogenes infection.
    Type: Application
    Filed: April 3, 2007
    Publication date: October 11, 2007
    Applicant: HANSA MEDICAL RESEARCH AB
    Inventors: Ulrich Von Pawel-Rammingen, Bjorn Johansson, Lars Bjorck