Patents Assigned to HAPILA GMBH
  • Patent number: 9095783
    Abstract: An arrangement and a method for producing high-purity crystals, such as temperature-sensitive pharmaceutical agents, in a countercurrent crystallization process. The arrangement comprises a plurality of crystallizers, mother liquor lines, each of which has a shut-off valve, and crystallization product lines, each of which has a shut-off valve, so that a mother liquor flow can be generated which is directed from a crystallizer to the second-next crystallizer in the direction of decreasing purity, and a crystallization product flow can be generated which is directed from a to dissolved crystallization product that is about to crystallize to the next crystallizer in the direction of higher purity.
    Type: Grant
    Filed: April 29, 2009
    Date of Patent: August 4, 2015
    Assignee: HAPILA GmbH
    Inventors: Detlef Grawe, Robert Eilers, Sabine Gliesing
  • Publication number: 20110065952
    Abstract: An arrangement and a method for producing high-purity crystals, such as temperature-sensitive pharmaceutical agents, in a countercurrent crystallization process. The arrangement comprises a plurality of crystallizers, mother liquor lines, each of which has a shut-off valve, and crystallization product lines, each of which has a shut-off valve, so that a mother liquor flow can be generated which is directed from a crystallizer to the second-next crystallizer in the direction of decreasing purity, and a crystallization product flow can be generated which is directed from a to dissolved crystallization product that is about to crystallize to the next crystallizer in the direction of higher purity.
    Type: Application
    Filed: April 29, 2009
    Publication date: March 17, 2011
    Applicant: HAPILA GMBH
    Inventors: Detlef Grawe, Robert Eilers, Sabine Gliesing