Patents Assigned to Harbor Branch Oceanographic Inst.
  • Synthetic compounds for treatment of inflammation
    Patent number: 6589975
    Abstract: Novel uses of biologically active bis-heterocyclic e.g. bis-indole alkaloid compounds which have improved activity are disclosed. Pharmaceutical compositions containing the compounds are also disclosed. Specifically, the novel utility pertains to the anti-immunogenic and neurogenic inflammatory properties exhibited by the bis-indole compounds and their analogs.
    Type: Grant
    Filed: August 5, 2002
    Date of Patent: July 8, 2003
    Assignees: The Regents of the University of California, Harbor Branch Oceanographic Inst.
    Inventors: Robert S. Jacobs, Claudia E. Moya, Amy E. Wright
  • Use for topsentin compounds and pharmaceutical compositions containing same
    Patent number: 5290777
    Abstract: A novel use for the class of biologically active bis-indole alkaloid compounds, which have been named topsentins, nortopsentins, or dragmacidins, pharmaceutical compositions containing them, methods of producing the compounds, and methods of using the compounds are disclosed. Specifically, the novel utility pertains to the anti-inflammatory properties exhibited by the bis-indole compounds and their analogs.
    Type: Grant
    Filed: February 24, 1993
    Date of Patent: March 1, 1994
    Assignees: Regents of the Univ. of California, Harbor Branch Oceanographic Inst. Inc.
    Inventors: Oliver J. McConnell, Gabriel Saucy, Robert Jacobs