Patents Assigned to HARC Therapeutics AG
  • Process for Manufacturing Stable Epinephrine
    Publication number: 20200297664
    Abstract: Epinephrine formulated in aqueous solvent at a basic pH of about 8.5 remains in solid state. My data show that epinephrine formulated at a pH of about 8.5 is surprisingly resistant to oxidation. I here teach how to formulate solid-state epinephrine in basic solution, and how to use solid-state epinephrine to make pharmaceutical dosage forms.
    Type: Application
    Filed: October 10, 2019
    Publication date: September 24, 2020
    Applicant: HARC Therapeutics AG
    Inventor: Robert CHISHOLM
  • High-pH solid-state epinephrine formulation
    Patent number: 10478406
    Abstract: Epinephrine formulated in aqueous solvent at a basic pH of about 8.5 remains in solid state. My data show that epinephrine formulated at a pH of about 8.5 is surprisingly resistant to oxidation. I here teach how to formulate solid-state epinephrine in basic solution, and how to use solid-state epinephrine to make pharmaceutical dosage forms.
    Type: Grant
    Filed: March 18, 2019
    Date of Patent: November 19, 2019
    Assignee: HARC Therapeutics AG
    Inventor: Robert Chisholm
  • High-pH Solid-State Epinephrine Formulation
    Publication number: 20190209495
    Abstract: Epinephrine formulated in aqueous solvent at a basic pH of about 8.5 remains in solid state. My data show that epinephrine formulated at a pH of about 8.5 is surprisingly resistant to oxidation. I here teach how to formulate solid-state epinephrine in basic solution, and how to use solid-state epinephrine to make pharmaceutical dosage forms.
    Type: Application
    Filed: March 18, 2019
    Publication date: July 11, 2019
    Applicant: HARC Therapeutics AG
    Inventor: Robert CHISHOLM