Abstract: The invention relates to a method of treating a subject who has cancer or a non-malignant tumor, the method comprising administering a therapeutically effective amount of a 18-20 member bi-polycyclic compound to the subject.
Type:
Grant
Filed:
July 3, 2019
Date of Patent:
March 23, 2021
Assignees:
Haro Pharmaceuticals Inc., The Royal Institution for the Advancement of Learning/ McGill University, Universite De Montreal
Inventors:
David Bettoun, Eduardo Martinez, James Gleason, Sylvie Mader, Shuo Xing
Abstract: The invention relates to a method of inhibiting loss of muscle mass or muscle function in a subject in need thereof, or a method of treating miofibers ex vivo, the method comprising administering a therapeutically effective amount of a 18-20 member bi-polycyclic compound to the subject or to the miofibers.
Type:
Grant
Filed:
July 3, 2019
Date of Patent:
August 25, 2020
Assignees:
Haro Pharmaceuticals Inc., The Royal Institution for the Advancement of Learning/McGill University, Universite De Montreal
Inventors:
David Bettoun, Eduardo Martinez, James Gleason, Sylvie Mader, Shuo Xing
Abstract: The invention relates to 18-20 member bi-polycyclic compounds, methods of making these compounds, and methods of using them in treating hyperproliferative disorders (e.g., cancer) and non-malignant tumors; promoting muscle formation; inhibiting muscle degeneration or the loss of muscle mass or muscle function; and myofibers ex vivo.
Type:
Grant
Filed:
December 6, 2017
Date of Patent:
August 13, 2019
Assignees:
Haro Pharmaceuticals Inc., The Royal Institution for the Advancement of Learning/ McGill University, Universite De Montreal
Inventors:
David Bettoun, Eduardo Martinez, James Gleason, Sylvie Mader, Shuo Xing