Abstract: A separator disk for use in centrifugal separation of components is designed to automatically position itself during separation at the interface between the supernatant and the remaining components. Preferably the interface is between plasma and red blood cells.

Abstract: A floating element for separating components of a physiological fluid comprises two parts that are relatively movable. The two parts define a prescribed volume between them when at their maximum separation, and one of the parts may be moved toward the other to express the fluid contained in the volume between the parts. The parts are made of materials having densities so that they assume a desired position in the fluid to allow selected components to be easily obtained and expressed.

Abstract: A separator disk for use in centrifugal separation of components is designed to automatically position itself during separation at the interface between the supernatant and the remaining components. Preferably the interface is between plasma and red blood cells.

Abstract: A separator disk for use in centrifugal separation of components is designed to automatically position itself during separation at the interface between the supernatant and the remaining components. Preferably the interface is between plasma and red blood cells.

Abstract: Apparatus for supporting a syringe includes a handle portion and a cradle. A clip is provided for connecting the plungers of two or more syringes, and two or more syringes are operated by placing one in the cradle and attaching the clip to the plungers for simultaneous operation of the plungers. The handle portion also forms a cavity for storing the clips. The apparatus is preferably used in combination with an applicator tip that combines the outputs from the two or more syringes.

Abstract: Devices for extracting bone marrow from a bone of a patient are disclosed. The device includes a housing defined in part by a cannula and a hollow needle disposed within the cannula. The hollow needle is movable axially relative to the cannula and extendable therefrom. The hollow needle is configured to aspirate bone marrow within a bone. A depth adjustment mechanism coupled to the hollow needle and the cannula is used to adjust the depth of the hollow needle relative to the cannula to control the distance of the needle within the bone. The device is attachable to an extraction device to extract bone marrow from the patient through the hollow needle. Methods of using these devices and methods of extracting bone marrow are also included.

Abstract: A floating separating element for use in centrifugal separation of components of a physiological fluid comprises a positioning part and a separating part, where the positioning part is designed to automatically assume a position in a supernatant and a separating part is positioned at a desired location with respect to the interface between the supernatant and heavier components. In preferred embodiments the physiological fluids are blood or bone marrow aspirate, and the heavier components comprise red blood cells. The positioning part comprises the majority of the mass of the separating element and is thin so that differences in the position of the separating element with respect to the interface are small compared to differences in the densities of the separated components, particularly the component comprising red blood cells. A method allows red blood cells to move the separating element during decanting to ensure complete decant of the supernatant.

Abstract: Adipose is obtained from aspirated adipose by centrifugal separation of adipose from tumescent fluids and oils released from damaged adipose cells. Aspirated adipose is placed in a container having therein a disk that floats on adipose and takes up the released oils whereby they are unlikely to remix with the adipose during handling after centrifugation. The disk also adheres to the adipose by entraining part of the adipose layer.

Abstract: A floating element for separating components of a physiological fluid comprises two parts that are relatively movable. The two parts define a prescribed volume between them when at their maximum separation, and one of the parts may be moved toward the other to express the fluid contained in the volume between the parts. The parts are made of materials having densities so that they assume a desired position in the fluid to allow selected components to be easily obtained and expressed.

Abstract: A separator disk for use in centrifugal separation of components is designed to automatically position itself during separation at the interface between the supernatant and the remaining components. Preferably the interface is between plasma and red blood cells.

Abstract: Devices for extracting bone marrow from a bone of a patient are disclosed. The device includes a housing defined in part by a cannula and a hollow needle disposed within the cannula. The hollow needle is movable axially relative to the cannula and extendable therefrom. The hollow needle is configured to aspirate bone marrow within a bone. A depth adjustment mechanism coupled to the hollow needle and the cannula is used to adjust the depth of the hollow needle relative to the cannula to control the distance of the needle within the bone. The device is attachable to an extraction device to extract bone marrow from the patient through the hollow needle. Methods of using these devices and methods of extracting bone marrow are also included.

Abstract: Methods and systems for collecting and processing bone marrow in a closed system are provided. The systems and methods include the use of a bone marrow aspiration needle and guide configured to puncture cortical bone. Tube assembly is in fluid flow communication with the bone marrow aspiration needle. A first syringe is in fluid flow communication with the tube assembly and the bone aspiration. A bone marrow aspirate collection container in fluid flow communication with the first syringe and the tube assembly. A second syringe is connected to the collection container, a bone marrow aspirate filter in fluid flow communication with the tube assembly to filter bone marrow aspirate from the first syringe into the collection container. At least one flow controller is configured to direct the flow of bone marrow aspirate between the aspiration needle, the first syringe and the collection container.

Abstract: A floating separating element for use in centrifugal separation of components of a physiological fluid comprises a positioning part and a separating part, where the positioning part is designed to automatically assume a position in a supernatant and a separating part is positioned at a desired location with respect to the interface between the supernatant and heavier components. In preferred embodiments the physiological fluids are blood or bone marrow aspirate, and the heavier components comprise red blood cells. The positioning part comprises the majority of the mass of the separating element and is thin so that differences in the position of the separating element with respect to the interface are small compared to differences in the densities of the separated compoments, particularly the component comprising red blood cells. A method allows red blood cells to move the separating element during decanting to ensure complete decant of the supernatant.

Abstract: A container (2) receives anhydrous material to be hydrated and hydrating fluids. The hydrating fluids are introduced into the container through a fluid port (8) by one or more containers having hydrating fluid. The hydrating fluids may be a mixture of fluids provided in any desired proportion. The hydrated material is then ejected from the container.

Abstract: A floating separating element for use in centrifugal separation of components of a physiological fluid comprises a positioning part and a separating part, where the positioning part is designed to automatically assume a position in a supernatant and a separating part is positioned at a desired location with respect to the interface between the supernatant and heavier components. In preferred embodiments the physiological fluids are blood or bone marrow aspirate, and the heavier components comprise red blood cells. The positioning part comprises the majority of the mass of the separating element and is thin so that differences in the position of the separating element with respect to the interface are small compared to differences in the densities of the separated components, particularly the component comprising red blood cells. A method allows red blood cells to move the separating element during decanting to ensure complete decant of the supernatant.

Abstract: A centrifuge has a rotor for receiving a disposable processing unit. The centrifuge is configured such that the motor is attached to an enclosure and the enclosure is supported on a base. The connection between the base and the enclosure is a vibration isolator, and the isolator is positioned such that its effective line of action aligns with the effective plane of rotation of the rotor. In accordance with another feature of the invention, the processing units are held in a decanting position by a decant ring that moves vertically but does not rotate. The ring engages the top of the processing unit during decant and the abrasion is minimal.

Abstract: A floating element for separating components of a physiological fluid comprises two parts that are relatively movable. The two parts define a prescribed volume between them when at their maximum separation, and one of the parts may be moved toward the other to express the fluid contained in the volume between the parts. The parts are made of materials having densities so that they assume a desired position in the fluid to allow selected components to be easily obtained and expressed.

Abstract: A floating separating element for use in centrifugal separation of components of a physiological fluid comprises a positioning part and a separating part, where the positioning part is designed to automatically assume a position in a supernatant and a separating part is positioned at a desired location with respect to the interface between the supernatant and heavier components. In preferred embodiments the physiological fluids are blood or bone marrow aspirate, and the heavier components comprise red blood cells. The positioning part comprises the majority of the mass of the separating element and is thin so that differences in the position of the separating element with respect to the interface are small compared to differences in the densities of the separated components, particularly the component comprising red blood cells. A method allows red blood cells to move the separating element during decanting to ensure complete decant of the supernatant.

Abstract: A centrifuge has a rotor for receiving a disposable processing unit. The centrifuge is configured such that the motor is attached to an enclosure and the enclosure is supported on a base. The connection between the base and the enclosure is a vibration isolator, and the isolator is positioned such that its effective line of action aligns with the effective plane of rotation of the rotor. In accordance with another feature of the invention, the processing units are held in a decanting position by a decant ring that moves vertically but does not rotate. The ring engages the top of the processing unit during decant and the abrasion is minimal.

Abstract: A separator disk for use in centrifugal separation of components is designed to automatically position itself during separation at the interface between the supernatant and the remaining components. Preferably the interface is between plasma and red blood cells.