Abstract: A system and a method for analyzing and evaluating genome data in the course of personalized medicine. In-memory technology is provided for processing of genome data and its real-time analysis as a holistic process in the course of personalized medicine. The cloud application helps physicians and researchers to identify the genetic roots for certain tumor types in the treatment of diseases correlating to genomic variants or mutations, such as cancer diseases. The system combines the latest international research results with patient-specific genomic data while eliminating the need for long-lasting manual searches of all dispositions in distributed international research and literature data sources.

Abstract: A computer implemented method for integrating data into a target database may include: providing a plurality of source databases which each may include a relational schema and data for integration into the target database; generating at least one complexity model based on the relational schema and data of each source database, each complexity model indicating at least one inconsistency between two or more of the data sources which may be require to be resolved to integrate the data from the data sources into the target database; and generating an effort model that may include an effort value for each inconsistency indicated by each complexity model, each effort value indicating at least one of a time period and a financial cost to resolve the inconsistency to integrate data from the data sources into the target database.

Abstract: A high performance, low-cost, gapped read alignment algorithm is disclosed that produces high quality alignments of a complete human genome in a few minutes. Additionally, the algorithm is more than an order of magnitude faster than previous approaches using a low-cost workstation. The results are obtained via careful algorithm engineering of the seeding based approach. The use of non-hashed seeds in combination with techniques from search engine ranking achieves fast cache-efficient processing. The algorithm can also be efficiently parallelized. Integration into an in-memory database infrastructure (IMDB) leads to low overhead for data management and further analysis.

Abstract: A federated in-memory database system (FIMDB) and a method for operating the same. The system comprises: A plurality of interconnected computing sites (LS), each installed with a local in-memory database instance, which is configured to connect to a FIMDB landscape instance; central computing infrastructure, provided by a service provider (SP), which grants access to algorithms managed by the service provider (SP) for execution on local data of the respective consuming computing site (LS); one or more communication channels (LSG1, LSG2), which are specifically adapted for connecting local and remote computing hard- and software via a digital communication channel; and configuration adjuster (CM), which are specifically adapted for configuring local hard- and software to connect to the FIMDB system (FIMDB) and for configuring local hard- and software in order to access algorithms managed by the service provider (SP) and execute them on the local computing hardware.

Abstract: The invention relates to a computer system and a corresponding method and a corresponding computer-readable medium according to the invention. The computer system is suitable for determining the result of a join. The computer system may be distributed system.

Abstract: The invention relates to a computer system for both online transaction processing and online analytical processing, comprising: a processor coupled to a database, the database comprising the database comprising: a main store (116) for storing records, a differential buffer (114) for receiving and buffering added or deleted or modified records, the differential buffer being coupled to the main store, a schema comprising records stored in the main store and records stored in the differential buffer, and a cache store (112) for caching a result of a query against the schema; and a cache controller (106) executable by the processor and communicatively coupled to the database, the cache controller being configured for: storing the result of the query in the cache store; receiving an analytical request; and determining, in response to the received request, an up-to-date result of the query by (216): accessing the cache store to obtain the cached result; determining the records of the schema that have been added or

Abstract: In general, methods and apparatus, including computer program products, implementing and using techniques for providing a discovery service in a unique identifier network are described. Said discovery service is suitable for tracking and tracing a query item represented by a unique identifier in a unique identifier network. In particular, a filter method for a containment-aware discovery service is described.

Abstract: In general, methods and apparatus, including computer program products, implementing and using techniques for providing a discovery service in a unique identifier network are described. Said discovery service is suitable for tracking and tracing a query item represented by a unique identifier in a unique identifier network. In particular, a search method for a containment-aware discovery service is described.

Abstract: A high performance, low-cost, gapped read alignment algorithm is disclosed that produces high quality alignments of a complete human genome in a few minutes. Additionally, the algorithm is more than an order of magnitude faster than previous approaches using a low-cost workstation. The results are obtained via careful algorithm engineering of the seeding based approach. The use of non-hashed seeds in combination with techniques from search engine ranking achieves fast cache-efficient processing. The algorithm can also be efficiently parallelized. Integration into an in-memory database infrastructure (IMDB) leads to low overhead for data management and further analysis.

Abstract: A system and a method for analyzing and evaluating genome data in the course of personalized medicine. In-memory technology is provided for processing of genome data and its real-time analysis as a holistic process in the course of personalized medicine. The cloud application helps physicians and researchers to identify the genetic roots for certain tumor types in the treatment of diseases correlating to genomic variants or mutations, such as cancer diseases. The system combines the latest international research results with patient-specific genomic data while eliminating the need for long-lasting manual searches of all dispositions in distributed international research and literature data sources.

Abstract: In general, methods and apparatus, including computer program products, implementing and using techniques for providing a discovery service in a unique identifier network are described. Said discovery service is suitable for tracking and tracing a query item represented by a unique identifier in a unique identifier network. In particular, a communication protocol for a containment-aware discovery service is described.

Abstract: A robust tenant placement and migration system, a process, and a respective controller for database-as-a-service environments are disclosed. Multiple tenants (T) are allocated on a set of in-memory database servers (S), such that workload changes depending on the tenants' behavior are considered, while maintaining strict service level objectives. The placement and migration are based on a migration command which, in turn, is based on an interleaved placement by interleaving tenants (T) across servers.

Abstract: In general, methods and apparatus, including computer program products, implementing and using techniques for providing a discovery service in a unique identifier network are described. Said discovery service is suitable for tracking and tracing a query item represented by a unique identifier in a unique identifier network. In particular, a communication protocol for a containment-aware discovery service is described.

Abstract: In one embodiment the present invention relates to a method for navigating within a database containing business objects. The method includes the steps of providing a preconfigured model comprising preconfigured business object types and preconfigured associations of the business object types, identifying a reference to a business object instance within a software object and determining a primary business object type corresponding to the business object instance, providing links to at least one secondary business object type associated with the primary business object type in accordance with the preconfigured business model, and retrieving from the database at least one attribute of at least one business object instance within the secondary business object type associated to the primary business object type in accordance with the preconfigured model. In this manner, a user may more easily navigate the database.