Abstract: The present disclosure relates to an anti-SNAP 25 antibody for inhibiting a SNARE complex, and a use thereof and, more specifically, to an anti-SNAP 25 antibody comprising heavy chain CDRs and light chain CDRs of specific sequences, or an antigen-binding fragment thereof. The anti-snap 25 antibody inhibits the formation of a SNARE complex, and thus is expected to be advantageously used for reducing or treating skin wrinkles.
Type:
Application
Filed:
October 14, 2020
Publication date:
August 3, 2023
Applicant:
HAUUL BIO
Inventors:
Hee-Jun NA, Yun-Suk LEE, Je-Ok YOO, Kwang-Soon LEE, Kangseung LEE, Seung Je MIN, Ji Won KANG
Abstract: The present invention relates to an anti-DKK-1 antibody promoting growth of human dermal papilla cells and a use thereof and, more particularly, to an anti-DKK-1 antibody comprising a heavy chain CDR and a light chain CDR of specific sequences, and an antigen-binding fragment thereof, wherein the anti-DKK-1 antibody promotes the growth of human dermal papilla cells and as such, is expected to be effectively used for promoting hair growth and preventing, alleviating, or treating hair loss.
Type:
Application
Filed:
September 27, 2021
Publication date:
March 23, 2023
Applicant:
HAUUL BIO
Inventors:
Hee-Jun NA, Yun-Suk LEE, Je-Ok YOO, Kwang-Soon LEE, Ji Young LEE
Abstract: The present invention relates to an anti-tyrosinase antibody for inhibiting tyrosinase and use thereof, and more particularly, to an anti-tyrosinase antibody including a heavy chain CDR and a light chain CDR of specific sequences, or an antigen-binding fragment thereof. The anti-tyrosinase antibody is expected to be effectively utilized for improving skin whitening or treating skin pigmentation disorders by inhibiting tyrosinase activity.
Type:
Application
Filed:
December 13, 2019
Publication date:
July 7, 2022
Applicant:
HAUUL BIO
Inventors:
Hee-Jun NA, Yun-Suk LEE, Je-Ok YOO, Kwang-Soon LEE, Kang Seung LEE, Seung Je MIN
Abstract: The present invention relates to an anti-VAMP2 antibody that inhibits SNARE complex and uses thereof, and more specifically, the present invention relates to an anti-VAMP2 antibody or antigen-binding fragments thereof comprising heavy and light chain CDRs of a specific sequence. The anti-VAMP2 antibody is expected to be useful for improving or treating skin wrinkles by inhibiting SNARE complex formation.
Type:
Application
Filed:
August 14, 2019
Publication date:
July 1, 2021
Applicant:
HAUUL BIO
Inventors:
Hee-Jun NA, Yun-Suk LEE, Je-Ok YOO, Kwang-Soon LEE, Kang Seung LEE, Seung Je MIN