Patents Assigned to HAV Vaccines Limited
  • Method of detecting subspecies
    Patent number: 11714085
    Abstract: A method of diagnosing or monitoring Mycobacterium avium subspecies paratuberculosis (MAP) infection, which method comprises detecting the presence of the polypeptide (MAP P900) encoded by the positive strand of IS900, or a fragment thereof, in a sample from a subject, wherein MAP P900, or a fragment thereof, is detected using an antibody, or an antigen-binding fragment thereof, that binds to MAP P900.
    Type: Grant
    Filed: June 15, 2021
    Date of Patent: August 1, 2023
    Assignee: HAV VACCINES LIMITED
    Inventor: John Hermon-Taylor
  • Immunogenic constructs
    Patent number: 8147850
    Abstract: The present invention relates to molecules, which can be used to induce a therapeutic or prophylactic immune response against MAP.
    Type: Grant
    Filed: January 14, 2011
    Date of Patent: April 3, 2012
    Assignee: HAV Vaccines Limited
    Inventors: John Hermon-Taylor, Timothy John Bull
  • Diagnostics and vaccines for mycobacterial infections of animals and humans
    Patent number: 8148136
    Abstract: This invention relates to the protein, Mycobacterium paratuberculosis acylase (mpa) and the gene encoding mpa, which we have identified in the pathogen Mycobacterium paratuberculosis Mptb (also designated Mycobacterium avium subspecies paratuberculosis MAP), and to their use in the diagnosis of Mptb/MAP infections in animals and humans, as well as their use as components of vaccines for the prevention and treatment of diseases caused by Mptb/MAP. The importance of an intact uninterrupted mpa gene as a determinant of pathogenicity in Mptb/MAP is recognized and the invention also provides attenuated strains of normally pathogenic Mptb/MAP and other mycobacteria in which mpa has been inactivated, for use as vaccines.
    Type: Grant
    Filed: March 18, 1999
    Date of Patent: April 3, 2012
    Assignee: HAV Vaccines Limited
    Inventors: John Hermon-Taylor, Timothy John Bull
  • Immunogenic Constructs
    Publication number: 20110129502
    Abstract: The present invention relates to molecules, which can be used to induce a therapeutic or prophylactic immune response against MAP.
    Type: Application
    Filed: January 14, 2011
    Publication date: June 2, 2011
    Applicant: HAV Vaccines Limited
    Inventors: John Hermon-Taylor, Timothy John Bull
  • Immunogenic constructs
    Patent number: 7892566
    Abstract: The present invention relates to molecules, which can be used to induce a therapeutic or prophylactic immune response against MAP.
    Type: Grant
    Filed: August 3, 2006
    Date of Patent: February 22, 2011
    Assignee: HAV Vaccines Limited
    Inventors: John Hermon-Taylor, Timothy John Bull