Patents Assigned to HBVtech LLC
  • Publication number: 20250101082
    Abstract: Disclosed herein is a method of treating human chronic hepatitis B virus infection by reducing or eliminating cccDNA in liver cell of an HBV infected patient for 3 months or longer.
    Type: Application
    Filed: December 21, 2022
    Publication date: March 27, 2025
    Applicant: HBVtech, LLC
    Inventor: Yong-yuan ZHANG
  • Patent number: 11136378
    Abstract: Disclosed are the methods of curing HBV infection and providing complete protection against HBV infection in a simplified HBV immunization schedule. The mechanistic basis for curing HBV infection is founded on the understanding that hepatitis B virus infection is established and prolonged by new rounds of infection with continuously produced viruses, which are not fully neutralized because of insufficient endogenous neutralizing antibodies. The methods of curing HBV infection including chronic HBV infection are aimed to block new rounds of HBV infection. The guidelines for establishing treatment regimens for curing HBV infection, include production or administration of sufficient level of HBV neutralizing antibodies in treated patients.
    Type: Grant
    Filed: November 17, 2016
    Date of Patent: October 5, 2021
    Assignee: HBVtech LLC
    Inventor: Yong-Yuan Zhang