Abstract: This disclosure provides a method for reducing or preventing the formation and/or accumulation of drusen in an eye of a mammalian subject in need thereof, the method comprising implanting one or more microporous devices into the eye, each device having a device body and an outer surface, wherein the microporous device is formed of a biocompatible elastomeric material and comprises a plurality of interconnected pores throughout the device body.
Abstract: Provided herein are implantable devices, such as vascular grafts and access port for hemodialysis, that include a microporous sheath layer having a corrugated outer surface, and use therefore for reducing the risk of infection or stenosis.
Type:
Grant
Filed:
August 13, 2019
Date of Patent:
August 25, 2020
Assignee:
Healionics Corporation
Inventors:
Andrew J. Marshall, Brandt Scanlan, Max Maginness, Adrienne Oda, Michael J. Connolly, Chad MacDonald
Abstract: Provided herein are implantable devices, such as vascular grafts and access port for hemodialysis, that include a microporous sheath layer having a corrugated outer surface, and use therefore for reducing the risk of infection or stenosis.
Type:
Grant
Filed:
August 25, 2017
Date of Patent:
September 24, 2019
Assignee:
HEALIONICS CORPORATION
Inventors:
Andrew J. Marshall, Brandt Scanlan, Max Maginness, Adrienne Oda, Michael J. Connolly, Chad MacDonald
Abstract: The disclosure provides granular forms of porous biomaterials and methods for forming and applying these biomaterials, including uses to promote vascularization and tissue ingrowth.
Type:
Grant
Filed:
March 3, 2010
Date of Patent:
January 6, 2015
Assignee:
Healionics Corporation
Inventors:
Max Maginness, Andrew Marshall, Christine L. Glaister, Michel Alvarez
Abstract: This disclosure provides implantable devices coated with microporous surface layers with macrotopographic features that improve bio-integration at the interface of the implantable devices and the surrounding tissue.
Type:
Grant
Filed:
December 18, 2012
Date of Patent:
February 11, 2014
Assignee:
Healionics Corporation
Inventors:
Andrew J. Marshall, Michel Alvarez, Max Maginness
Abstract: This disclosure provides implantable devices coated with microporous surface layers with macrotopographic features that improve bio-integration at the interface of the implantable devices and the surrounding tissue.
Type:
Application
Filed:
December 18, 2012
Publication date:
September 12, 2013
Applicant:
HEALIONICS CORPORATION
Inventors:
Andrew J. Marshall, Michel Alvarez, Max Maginness
Abstract: This disclosure provides implantable devices coated with microporous surface layers with macrotopographic features that improve bio-integration at the interface of the implantable devices and the surrounding tissue.
Type:
Grant
Filed:
April 8, 2011
Date of Patent:
February 12, 2013
Assignee:
Healionics Corporation
Inventors:
Andrew J Marshall, Michel Alvarez, Max Maginness
Abstract: The disclosure provides granular forms of porous biomaterials and methods for forming and applying these biomaterials, including uses to promote vascularization and tissue ingrowth.
Type:
Application
Filed:
March 3, 2010
Publication date:
January 24, 2013
Applicant:
HEALIONICS CORPORATION
Inventors:
Max Maginness, Andrew Marshall, Christine L. Glaister, Michel Alvarez
Abstract: This disclosure provides implantable devices coated with microporous surface layers with macrotopographic features that improve bio-integration at the interface of the implantable devices and the surrounding tissue.
Type:
Application
Filed:
April 8, 2011
Publication date:
October 20, 2011
Applicant:
HEALIONICS CORPORATION
Inventors:
Andrew J. Marshall, Michel Alvarez, Max Maginness
Abstract: Described herein is an applicator tool for sleeving an elongated device, the tool including a hollow, continuous base section, at least two arm members extending laterally from the base section, the arm members and the base section defining an axial passage extending therethrough, and an elastomeric sleeve positioned over a portion of an outer peripheral surface of the arm members and axially aligned with the axial passage, wherein each arm member is radially flexible such that the axial passage can be radially compressed or expanded, and wherein the axial passage allows for a movable positioning of the elongated device.