Abstract: A method of performing a diagnosis by acquiring data includes receiving an indication of a diagnostic hypothesis, sequentially outputting questions of a structured set of questions related to the diagnostic hypothesis for the indication, receiving a reply corresponding to each question that is output, for each question that is output, generating a respective set of data pertaining to the question and the corresponding reply for the question and formatting the respective set of data into a plurality of record sets for the question, and storing the plurality of record sets for each question within a database in an entry associated with the subject and the diagnostic hypothesis to which the question is related. The questions of the structured set of questions for each indication are dynamically selected for outputting based on the corresponding replies received for the questions.