Patents Assigned to Health Innovation Ventures B.V.
  • Prodrugs and methods of use thereof
    Patent number: 10202408
    Abstract: The invention relates to compounds of use as targeted cytotoxic agents and methods of use thereof. In particular, the invention relates to prodrugs that are substantially resistant to human AKR1C3 enzyme metabolism, methods of cell ablation using said compounds and methods of treatment of cancer and other hyperproliferative disorders using said compounds.
    Type: Grant
    Filed: January 22, 2018
    Date of Patent: February 12, 2019
    Assignee: Health Innovation Ventures B.V.
    Inventors: Jeffrey Bruce Smaill, Adam Vorn Patterson, Amir Ashoorzadeh, Christopher Paul Guise, Alexandra Marie Mowday, David Francis Ackerley, Elsie May Williams, Janine Naomi Copp
  • Prodrugs and methods of use thereof
    Patent number: 9873710
    Abstract: The invention relates to compounds of use as targeted cytotoxic agents and methods of use thereof. In particular, the invention relates to prodrugs that are substantially resistant to human AKR1C3 enzyme metabolism, methods of cell ablation using said compounds and methods of treatment of cancer and other hyperproliferative disorders using said compounds.
    Type: Grant
    Filed: October 31, 2016
    Date of Patent: January 23, 2018
    Assignee: Health Innovation Ventures B.V.
    Inventors: Jeffrey Bruce Smaill, Adam Vorn Patterson, Amir Ashoorzadeh, Christopher Paul Guise, Alexandra Marie Mowday, David Francis Ackerley, Elsie May Williams, Janine Naomi Copp
  • Prodrugs and methods of use thereof
    Patent number: 9505791
    Abstract: The invention relates to compounds of use as targeted cytotoxic agents and methods of use thereof. In particular, the invention relates to prodrugs that are substantially resistant to human AKR1C3 enzyme metabolism, methods of cell ablation using said compounds and methods of treatment of cancer and other hyperproliferative disorders using said compounds.
    Type: Grant
    Filed: August 22, 2013
    Date of Patent: November 29, 2016
    Assignee: Health Innovation Ventures B.V.
    Inventors: Jeffrey Bruce Smaill, Adam Vorn Patterson, Amir Ashoorzadeh, Christopher Paul Guise, Alexandra Marie Mowday, David Francis Ackerley, Elsie May Williams, Janine Naomi Copp