Abstract: A method for production of solid water particles for homeopathy uses principles of quantum physics to from a concentrated solid water particle solution. A homeopathic ingredient solution is diluted in purified water in an inert gas environment. The dilution occurs as infinitesimal doses, in which the solution is repetitively diluted in water past the point where few molecules from the solution remain. An electrical field is applied to align the water molecules for formation of a large clump of solid water particles. Alternating phases of ultrasonic vibrations break down the large clump into small clusters of solid water particles. The vibration is followed by periods of rest, whereby the small clusters grow into successively larger clumps by absorbing water molecules. The vibrations and resting are repeated in cycles until a desired concentration of solid water particles form in the solid water particle solution.
Abstract: A pulmonary access device comprises an elongated shaft having a proximal shaft section, a bendable shaft section, a distal shaft section, and a distal tip. The pulmonary access device further comprises an elongated sheath having a proximal sheath section, a malleable distal sheath section, and working channel. The working channel is configured for slidably receiving the elongated shaft. The pulmonary access device further comprises a handle assembly including a handle body. The handle body is affixed to a proximal end of the elongated shaft. The handle body is removably affixed to a proximal end of the elongated sheath.
Abstract: A digital radiographic detector includes a planar multi-layered core with a two-dimensional array of photo-sensitive cells. A five-sided, integrally formed, rigid enclosure having one open side is configured to receive the multi-layered core through the open side. The planar multi-layered core comprises a foam layer having a recessed pocket on one major side thereof shaped in the form of a metal ground plane positioned in the recessed pocket.
Abstract: A physiological signal monitoring method includes steps that involve: acquiring samples of at least one digitized physiological signal through the use of a device carried by a user; detecting events within the digitized physiological signal by means of the device and extracting characteristics of the detected events by means of the device; searching for an anomaly in the events and characteristics of the extracted events by means of the device; and, via an encrypted wireless link, transmitting the digitized physiological signal by means of the device to a server via a mobile terminal when an anomaly is detected. If an anomaly is not detected, the digitized physiological signal is deleted by the device.
Abstract: Mechanisms for pulling a tensile member a predetermined distance from a medical device having an intracorporeal end and an extracorporeal end are disclosed. Such mechanisms may be safely operated using a robot, two hands, or in some embodiments, only one hand. Such mechanisms may include one or more cams, drums, or pulley-like members and a lever, and may be physically coupled to an extracorporeal portion of the medical device.
Type:
Grant
Filed:
June 22, 2011
Date of Patent:
June 1, 2021
Assignee:
CARDINAL HEALTH SWITZERLAND 515 GMBH
Inventors:
Cesar Rincon, Matthew Krever, Daniel Olsen, Edward Johnson
Abstract: A method for producing a chassis web for a disposable pant article, the method including feeding a first continuous base web in a machine direction; attaching a continuous elastic waistband component to the first base web in an attachment area extending in the machine direction; attaching a second continuous base web to the first continuous base web and the continuous waistband component, covering at least the continuous waistband component, thereby forming a compound base web having first and second side edges, the attachment area being spaced apart from at least one of the first and second side edges of the compound base web; severing the compound base web and the attached waistband component by cutting; shifting positions of the first panel web and the second panel web in a cross machine direction; forming a coherent chassis web.
Abstract: The present invention provides an antigenic composition for use as a mycobacterial vaccine, said composition comprising (i) a first mycobacterial antigenic polypeptide, wherein said first mycobacterial antigenic polypeptide comprises a polypeptide sequence having at least 70% amino acid sequence identity to the amino acid sequence of SEQ ID NO: 6, 12, 2, 18, 8, 10, 16, 4, or a fragment thereof having at least 50 consecutive amino acids thereof; or (ii) a first mycobacterial polynucleotide, wherein said first mycobacterial polynucleotide comprises a polynucleotide sequence encoding said first mycobacterial antigenic polypeptide, or wherein said first mycobacterial polynucleotide comprises a polynucleotide sequence selected from SEQ ID NO: 5, 11, 1, 17, 7, 9, 15, 3.
Type:
Grant
Filed:
August 8, 2017
Date of Patent:
June 1, 2021
Assignee:
SECRETARY OF STATE FOR HEALTH AND SOCIAL CARE
Abstract: A method for characterizing a brain electrical signal comprising forming a temporo-spectral decomposition of the signal to form a plurality of time resolved frequency signal values, associating each instance of the signal value with a predetermined function approximating a neurological signal to form a table of coefficients collectively representative of the brain electrical signal.
Type:
Grant
Filed:
January 7, 2019
Date of Patent:
June 1, 2021
Assignee:
University Health Network
Inventors:
César Marquez Chin, Kathryn Atwell, Milos R. Popovic
Abstract: The present invention is directed toward a detection architecture for use in implantable cardiac rhythm devices. The detection architecture of the present invention provides methods and devices for discriminating between arrhythmias. Moreover, by exploiting the enhanced specificity in the origin of the identified arrhythmia, the detection architecture can better discriminate between rhythms appropriate for device therapy and those that are not.
Type:
Grant
Filed:
December 20, 2018
Date of Patent:
June 1, 2021
Assignee:
CAMERON HEALTH, INC.
Inventors:
Alan H. Ostroff, Jay A. Warren, Gust H. Bardy
Abstract: Provided are pyrroloquinolin compounds of formula (1) or (II). In certain aspects, the pyrroloquinolin compounds are therapeutic, e.g., for treating a cell proliferative disorder. Also provided are conjugates that include the pyrroloquinolin compounds of the present disclosure. Compositions, e.g., pharmaceutical compositions, that include the pyrroloquinolin compounds and conjugates of the present disclosure are also provided. Further provided are therapeutic methods involving the administration of the pyrroloquinolin compounds, conjugates or compositions of the present disclosure. Kits that include the pyrroloquinolin compounds, conjugates or compositions are also provided.
Type:
Grant
Filed:
March 13, 2018
Date of Patent:
June 1, 2021
Assignees:
The Regents of the University of California, Henry Ford Health System
Inventors:
Phillip Crews, Frederick A. Valeriote, Sheng Lin, Erin P. McCauley, Nicholas Lorig-Roach, Karen Tenney
Abstract: A load-balancing server having at least one memory comprising instructions, at least one processing device configured for executing the instructions and a load-balancing module, coupled to the at least one memory, the at least one processing device, and at least one data transformation module, and configured for determining a first amount of computing resources for allocating to the at least one data transformation module using a load-balancing technique, the at least one data transformation module coupled to the at least one memory, the at least one processing device, and the load-balancing module.
Type:
Grant
Filed:
March 27, 2018
Date of Patent:
June 1, 2021
Assignee:
ATOS DIGITAL HEALTH SOLUTIONS, INC.
Inventors:
Kiran Kumar Kodeboina, Cynthia G. Nicholas, Brenda S. Ikerd
Abstract: One aspect of the invention provides an imaging method including: (a) acquiring a first fluorescent image of an object of interest impregnated with fluorescent nanodiamonds; (b) applying a magnetic field to the fluorescent nanodiamonds in order to decrease fluorescence of the fluorescent nanodiamonds; (c) acquiring a second fluorescent linage of the object of interest; and (d) subtracting the second fluorescent linage from the first fluorescent image to produce a resulting image. Another aspect of the invention provides an imaging method including: (a) applying a time-varying magnetic field to an object of interest impregnated with fluorescent nanodiamonds to modulate the fluorescence of the fluorescent nanodiamonds; (b) acquiring a plurality of fluorescent images of the object of interest; and (c) for each corresponding pixel in the plurality of fluorescent images, calculating a fluorescence intensity using a lock-in technique.
Type:
Grant
Filed:
August 22, 2016
Date of Patent:
June 1, 2021
Assignee:
The United States of America, as represented by the Secretary, Department of Health and Human Services
Abstract: A system and method are disclosed for tracking animals, which may include production animals as well as pets. The system and method may comprise a tag system that is attached to an animal that generally has at least a near-field-communication (NFC) tag. The tag system comprises at least an NFC tag and a radio-frequency identification (RFID) tag. For NFC tags, such tags may be read with a portable computing device, such as a mobile telephone running NFC reader application software. The phone may communicate with a communications network and ultimately a computer server in order to relay information received from a respective electronic tag. The electronic tags may be fastened, embedded, or ingested by an animal. The electronic tags may be part of a mechanical coupling. Each mechanical coupling may comprise a different structure depending on the whether the tags are fastened to, embedded in, or ingested by the animal.
Type:
Grant
Filed:
June 14, 2019
Date of Patent:
June 1, 2021
Assignee:
BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC.
Inventors:
Pierre-Emmanuel Deliou, Michael Edward Hay Hutton
Abstract: The present invention relates to a novel coloring material including a polyamide powder and/or a polyurethane powder and a water-soluble dye. The coloring material of the present invention allows a water-soluble dye to be used in anhydrous formulations. Thereby, the range of use of dyes may be widened, reflectance may be excellent, and fluorescence properties may be obtained. Accordingly, the present invention may broaden the spectrum of cosmetic coloring materials used in limited applications in the cosmetic field.
Type:
Grant
Filed:
October 15, 2018
Date of Patent:
June 1, 2021
Assignee:
LG HOUSEHOLD & HEALTH CARE LTD.
Inventors:
Hong Ha Son, Kyong Seob Kim, Khee Hwan Choi, Ko Eun Park
Abstract: According to one aspect of the present disclosure, a stationary exercise apparatus which not only can a user exercise alternately with one leg lifting and the other leg pressing but the exercising paths thereof are capable of being adjusted so that the user is capable of exercising with different postures and motions and having more abundant exercise types. For the sake of safety, stability, and convenience, the supporting portions for the user to step on have specific orientation angles and don't rotate arbitrarily to different positions at every point of the exercising path.
Abstract: The invention relates to methods, compounds, compositions and vehicles for delivering 3-amino-1-propanesulfonic acid (3APS) in a subject, preferably a human subject. The invention encompasses compound that will yield or generate 3APS, either in vitro or in vivo. Preferred compounds include amino acid prodrugs of 3APS for use, including but not limited to the prevention and treatment of Alzheimer's disease.
Type:
Grant
Filed:
April 24, 2020
Date of Patent:
June 1, 2021
Assignee:
Bellus Health Inc.
Inventors:
Xianqi Kong, Mohamed Atfani, Benoit Bachand, Abderrahim Bouzide, Stephane Ciblat, Sophie Levesque, David Migneault, Isabelle Valade, Xinfu Wu, Daniel Delorme
Abstract: An image display system is provided comprised of a virtual window system that creates a visual coherency between the patient's anatomical images and the actual patient by aligning the image on the display to the patient and then presenting the image to the user in a way that feels as if the user is looking directly into the patient through the display. The image shown within the image display system is dependent upon the position of the image display apparatus and the position of the user so that the display orientation of the image may be biased slightly toward the user to improve ergonomics and usability.
Type:
Grant
Filed:
May 23, 2014
Date of Patent:
June 1, 2021
Assignee:
Auris Health, Inc.
Inventors:
Daniel Wallace, Gregory Stahler, Aaron Grogan
Abstract: Antibodies and antigen binding fragments that specifically bind to P. falciparum circumsporozoite protein and neutralize P. falciparum are disclosed. Nucleic acids encoding these antibodies, vectors and host cells are also provided. The disclosed antibodies, antigen binding fragments, nucleic acids and vectors can be used, for example, to inhibit a P. falciparum infection.
Type:
Grant
Filed:
February 12, 2018
Date of Patent:
June 1, 2021
Assignees:
The United States of America as represented by the Secretary, Department of Health and Human Services, Sanaria Inc.
Inventors:
Robert Seder, Neville Kisalu, Azza Idris, Barbara Flynn, Stephen Hoffman