Abstract: The present invention in one aspect relates to a method for treating cancer or enhancing a cancer treatment, the method comprising inhibiting the expression of an oligonucleotide encoding for a protein selected from the group consisting of OLFM4, SP5, TOB1, ARID1A, FBN1 and HAT1, by administering to a mammal in need of cancer treatment an effective amount of at least one silencing oligonucleotide comprising a binding motif for binding to the oligonucleotide encoding for a protein.

Abstract: Exothermic and/or endothermic chemical reactions in combination with phase change materials can produce output temperature(s) within strict tolerances without requiring expensive and complicated external equipment to generate and maintain an output temperature. Similarly, an exothermic phase change material, which generates heat as a consequence of crystallizing a supercooled liquid, can generate heat at a constant temperature, without requiring expensive and complicated external equipment, as a consequence of the liquid form of the exothermic phase change material being in equilibrium with the solid form of the exothermic phase change material. Numerous biological and chemical processes and/or diagnostic devices require a constant temperature or temperatures for set periods of time.

Abstract: A defibrillation system having a physiological parameter measuring device for measuring parameters that may indicate a need for a defibrillator; an emergency level detector in communication with the physiological parameter measuring device for detecting emergency level physiological parameters; and a notification device in communication with the emergency level detector for providing notice of the detection of an emergency-level physiological parameter to a caregiver who can then utilize a defibrillator.

Abstract: Universal internet access to a patient's critical medical records is obtainable by creating an anonymous medical homepage for each patient which is devoid of any personal identifiers. The anonymous medical homepage is hosted on a centralized data server which receives medical information from a participating physician's electronic medical records program. At the time of an office or consultation visit, EMR data is captured by the data center and processed so as to append critical patient medical information to the patient's anonymous homepage. The owner of the anonymous homepage is identified solely by a pseudoname and password, such that the patient's identity is maintained in confidence. A medical alert bracelet or medical alert card, containing the patient's pseudoname and password, gives notice and grants access to an emergency physician in cases where the patient is unconscious or otherwise unable to communicate a scientifically rigorous and detailed medical history.

Abstract: Branched nanowire preparation methods, compositions, and articles are disclosed. Such branched nanowires are useful for electronics and optical applications.

Abstract: A substantially pure or isolated oligodeoxynucleotide of at least 10 nucleotides is disclosed, wherein the oligodeoxynucleotide comprised a sequence represented by either formula: 5? N1N2N3T-CpG-WN4N5N6 3? wherein the CpG motif is unmethylated, W is A or T, and N1, N2, N3, N4, N5, and N6 are nucleotides, or the formula: 5? RY-CpG-RY 3? wherein the central CpG motif is unmethylated, R is A or G, and Y is C or T, as well as an oligodeoxynucleotide delivery complex and a pharmacological composition comprising the present inventive oligodeoxynucleotide, and a method of inducing an immune response by administering the present inventive oligodeoxynucleotide to a host. In some embodiments, the oligodeoxynucleotide includes the nucleic acid sequences set forth as SEQ ID NO: 137.

Abstract: A device for sustaining a plasma in a torch is provided. In certain examples, the device comprises a first electrode configured to couple to a power source and constructed and arranged to provide a loop current along a radial plane of the torch. In some examples, the radial plane of the torch is substantially perpendicular to a longitudinal axis of the torch.

Abstract: The disclosure provides methods for increasing genome stability of an embryonic stem (ES) cell or induced pluripotent stem (iPS) cell, increasing telomere length in an ES or iPS cell, or both, for example by contacting an ES or iPS cell with an agent that increases expression of Zscan4 in the cell. Methods for increasing the genome stability in a population of ES or iPS cells, increasing telomere length in a population of ES or iPS cells, or both, are provided, for example by selecting Zscan4+ ES or iPS cells from the population of ES or iPS cells (which can include both Zscan4+ and Zscan4? ES or iPS cells). Therapeutic methods of using ES or iPS cells expressing Zscan4 are also provided. Further provided are methods of treating cancer by administering a Zscan4 polynucleotide or Zscan4 polypeptide. Also provided are methods of inducing differentiation of isolated ES or iPS cells into germ cells.

Abstract: A handheld device workout coach system includes: at least a handheld device installed therein with a coaching program and having a near field communication (NFC) module and a ID recognition data; at least a fitness device having a master control unit, a near field communication (NFC) module corresponding in position and function to the master control unit, and a platform; and a server stored therein with workout prescriptions downloadable by the at least a handheld device and available to the coaching program. The master control unit has an equipment recognition data. The handheld device and the fitness device get connected by near field communication (NFC) technology as soon as the handheld device is positioned on the platform of the fitness device and recognize each other to thereby execute the coaching program instantly and automatically, such that a corresponding one of the workout prescriptions instructs a user to take exercise.

Abstract: A messaging system for a health care community includes a private network. Electronic medical records are accessible via the private network. A calendar system includes appointments of patients with medical providers. An encrypted firewall and subscriber directory limits access to the private network so that only subscribers to the private network have access to the private network. Subscribers are identified by mobile phone numbers or extensions.

Abstract: The invention discloses a method by which the health care professional or patient may draw upon historical medical data concerning patients similarly situated in medical condition, to assist him/her in deciding on a clinical intervention procedure to select. This method is specifically tailored to the patient, as data is provided and evaluated from only similarly situated patients, and provides an expectation of potential outcome of the patient should one or the other of the options be selected. The invention further provides a database that may be used in order to provide this comparison based evaluation method. A computer based software system is further disclosed that implements the method. The invention more speiocifically provides a method by which a post-coronary event patient may make an informed decision of which post-coronary revascularization procedure to undergo in the future management of his disease.

Abstract: An elliptical exercise apparatus includes a base frame with two supporting frames, two swing sleeves each pivotally connected with one supporting frame, two sliding arms each having a top portion slidably inserted through one swing sleeve and a bottom portion extending transversely inwardly and coupled with a treadle, two swing arms each having an end pivotally coupled with the base frame, and two sliding sleeves each axially slidably sleeved onto one swing arm and pivotally connected with the bottom portion of one sliding arm through a pivot. A rotational shaft is transversely and rotationally coupled with the base frame. Two links each have an end vertically coupled with one of two ends of the rotational shaft, and an opposite end pivotally connected with a lower portion of one of the sliding sleeves.

Abstract: The present invention provides gene sets the expression of which is important in the diagnosis and/or prognosis of breast cancer.

Abstract: The present invention provides a compound of the formula (I) or (II, wherein R1 is H, alkyl, alkenyl or aryl, R2 is H, alkyl or aryl, R3 is H, a alkyl, alkenyl or aryl, R4 and R4-R8 are independently R10, C(O)R10 or SO2R10, wherein R10 is H, alkyl, alkenyl or aryl, and R9 is R9a, C(O)R9a or SO2R9a, wherein R9a is H, alkyl, alkenyl or aryl. R9a can be unsubstituted or substituted with one or more oxo(?O), OR9b, OC(O)R9b, OSO2R9b, NHR9b, NHC(O)R9b and NHSO2R9b groups. R9b is H, alkyl, alkenyl, or aryl. R9b can be unsubstituted or substituted with one or more groups such as oxo(?O), OR9c, CO2R9c, CO2R9c and OC(O)R9c. R9c is H, or a unsubstituted or substituted alkyl, alkenyl or aryl. The present invention further provides a composition comprising at least one compound of the present invention and a pharmaceutically acceptable carrier, alone or in combination with at least one additional active agent.

Abstract: A method of treating cancer in an immune-privileged site of a subject in need thereof is provided. The method comprises systemically administering to an area outside the immune-privileged site of the subject, a therapeutically effective amount of naive, viable cells of a tumor of the subject, the tumor being in the immune-privileged site so as to generate an immune response in the subject, thereby treating the cancer in the immune-privileged site of the subject.

Abstract: A method for providing decision support includes using a programmed computer to input a regression model specification, and to repeat the input a plurality of times to obtain and store a plurality of regression model specifications. The method further includes using the programmed computer to analyze selected regression model specifications to determine at least one of common variables and functions of common variables, to thereby determine a reduced-redundancy request for input of variables, when a plurality of the stored regression model specifications are selected for use.

Abstract: Methods of preparing metal nanowire are disclosed that employ quaternary phosphonium salts. Such processes can produce long and thin nanowires. Compositions and articles comprising such nanowires are useful in electronics applications.

Abstract: There is provided an in vitro method of detecting human papillomavirus nucleic acid in a sample, comprising: (a) contacting said sample with forward and reverse oligonucleotide primers, wherein said primers bind to target sites in the human papillomavirus L1 gene, or the complement thereof, under conditions suitable to promote amplification of a portion of said human papillomavirus L1 gene or complement, thereby generating an amplicon; (b) contacting said amplicon with a probe, wherein the probe binds to a target site within said amplicon; and (c) detecting binding of said probe to said amplicon; wherein said forward primer binds to a target site having the sequence SEQ ID NO: 1; and wherein said reverse primer binds to a target site having the sequence SEQ ID NO: 2.

Abstract: Ultraviolet radiation (UVR) has profound effects on human skin. However, its effects on the global transcriptome in vivo have not been well characterized. In addition, the contribution of the UVA component of UVR has not been previously assessed in vivo. Disclosed herein is the identification of sets of genes that are either up-regulated or down-regulated in response to UVA exposure. The gene sets described herein can be used to accurately identify skin samples that have been exposed to UVA and to assess the ability of a sun protection product to block the effects of UVA.

Abstract: Methods of assessing genomic instability in breast cancer tissue by measuring the expression level of genes CDKN2A, SCYA18, STK15, NXF1, cDNA Dkfzp762M127, p28 KIAA0882, MYB, Human clone 23948, RERG, HNF3A, and ACADSB or a nucleic acid sequence comprising about 90% or greater sequence identity to SEQ ID NO: 21 in breast cancer tissue, an array suitable for use in such methods, and related methods and compositions.