Abstract: A system includes a smartphone contained within a medication adherence case, the medication adherence case including a repository and a hinged access door to the repository, a wireless network linking the smartphone to a content data network (CDN), the CDN including a medication adherence server, and an application residing in the smartphone that sends data to a medical adherence process in the medical adherence server upon receiving a signal generated from a communication device residing in the hinged access door that indicates the hinged access door has been opened.