Patents Assigned to Hebrew University
  • Publication number: 20230172195
    Abstract: The present invention provides microcapsules encapsulating hydrophilic or hydrophobic active agents in an inorganic shell, processes for their preparation and compositions comprising them.
    Type: Application
    Filed: November 22, 2018
    Publication date: June 8, 2023
    Applicant: Yissrm Research Developmet Company of The Hebrew University of Jerusalem Ltd.
    Inventors: Raed ABU-REZIQ, Charlie BATARSEH, Ahmad ZAROUR, Yafit SCHNELL, Amani ZOABI, Suzana NATOUR, Suheir OMAR, Esti WESS
  • Publication number: 20230172929
    Abstract: The technology disclosed herein concerns compounds capable of binding to CB1Rs in the periphery and not in the CNS.
    Type: Application
    Filed: August 6, 2020
    Publication date: June 8, 2023
    Applicant: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Joseph TAM, Amiram GOLDBLUM, Shayma EL-ATAWNEH, Shira HIRSH
  • Publication number: 20230174924
    Abstract: A method of culturing bacteria of the Bacilli class is disclosed. The method comprises: (a) adding the bacteria to a medium comprising pasteurized starch fibers of a legume of a leguminous plant, and (b) culturing the bacteria under conditions that promote generation of a biofilm of the bacteria on the starch fibers.
    Type: Application
    Filed: January 18, 2023
    Publication date: June 8, 2023
    Applicants: The State of Israel, Ministry of Agriculture & Rural Development, Agricultural Research Organization, Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Moshe SHEMESH, Shmuel GALILI, Ram REIFEN
  • Publication number: 20230180490
    Abstract: Provided is a perovskite-based photovoltaic device including a layered scaffold material and at least one perovskite material interpenetrating the layered scaffold, wherein the at least one perovskite layer is removable and regenerable.
    Type: Application
    Filed: March 31, 2021
    Publication date: June 8, 2023
    Applicant: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Lioz ETGAR, Avraham SCHNEIDER, Ariel EFRATI
  • Patent number: 11666618
    Abstract: Provided are methods for selective extraction of cannabinoids, for example cannabidiol (CBD), from a plant source, by using tailored extraction media.
    Type: Grant
    Filed: September 28, 2017
    Date of Patent: June 6, 2023
    Assignee: YISSUN RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD.
    Inventors: Nissim Garti, Sharon Garti Levi, Rotem Edri
  • Patent number: 11660270
    Abstract: Compositions comprising nanoparticles are described herein. At least a portion of the nanoparticles comprises a lipid and/or polymer which is water-insoluble, and an agent incorporated in the lipid and/or polymer. The nanoparticles are optionally associated with a surface of water-soluble particles which comprise a water-soluble compound. The polymer is optionally a polyanhydride. Further described herein are processes for preparing such compositions, comprising contacting a solution comprising the lipid and/or polymer dissolved in a non-aqueous solvent with an anti-solvent (in which the lipid and/or polymer and agent are insoluble) which is miscible with the non-aqueous solvent. Further described herein are uses of the compositions for nasal administration, and devices configured for nasal administration of the composition upon atomization.
    Type: Grant
    Filed: July 20, 2018
    Date of Patent: May 30, 2023
    Assignees: INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION, YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD.
    Inventors: Domb Abraham Jacob, Michael Kubek
  • Publication number: 20230157896
    Abstract: The present invention relates to a device for repair of a region within an ear via a natural orifice, the device comprising a body. The body comprises a first port for visibly identifying the region to be sealed, the region being inside the ear; and a second port through which a seal can be introduced into the ear through the device. The region comprises a perforation of a tympanic membrane of the ear and the device is a speculum. The present invention also relates to method for repairing a perforation in a tympanic membrane using the same device.
    Type: Application
    Filed: March 11, 2021
    Publication date: May 25, 2023
    Applicants: National University of Singapore, Hadasit Medical Research Services And Development Ltd, Yissum Research Development Company of the Hebrew University of Jerusalem Ltd
    Inventors: Menachem Gross, Shlomo Magdassi, Yin Chiang Boey, Ngeow Khing Chia
  • Publication number: 20230148632
    Abstract: The present invention provides processes for producing food products, particularly juice beverages, with reduced sugar content enriched with dietary fibers and the food products produced. The processed food products are low in calories while preserving the palatable test of the starting material, and contain beneficial amount of dietary fibers. The processed food product further contains sorbitol and gluconic acid.
    Type: Application
    Filed: January 3, 2023
    Publication date: May 18, 2023
    Applicant: YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD,
    Inventors: Roni SHAPIRA, Eran BALACHINSKY
  • Patent number: 11632972
    Abstract: The invention relates to a process for treating food, in particular for curing meat, comprising adding to the food a compound of Formula III, which is a derivative of S-nitroso-cysteine. Use of the compound of Formula III as food preservative and compositions for curing meat are also provided by the invention.
    Type: Grant
    Filed: July 31, 2018
    Date of Patent: April 25, 2023
    Assignee: YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD.
    Inventors: Oren Tirosh, Joseph Kanner, Adi Spaizer-Katzenelson
  • Patent number: 11630266
    Abstract: An optical switching device (20) includes a substrate (39) and first and second optical waveguides (23, 25) having respective first and second tapered ends (62, 64), which are fixed on the substrate in mutual proximity one to another. A pair of electrodes (36, 38) is disposed on the substrate with a gap therebetween. A cantilever beam (32) is disposed on the substrate within the gap and configured to deflect transversely between first and second positions within the gap in response to a potential applied between the electrodes. A third optical waveguide (21) is mounted on the cantilever beam and has a third tapered end (60) disposed between the first and second tapered ends of the first and second waveguides, so that the third tapered end is in proximity with the first tapered end when the cantilever beam is in the first position and is in proximity with the second tapered end when the cantilever beam is in the second position.
    Type: Grant
    Filed: January 17, 2019
    Date of Patent: April 18, 2023
    Assignees: YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY LTD., MELLANOX TECHNOLOGIES, LTD.
    Inventors: Eran Aharon, Dan Mark Marom, Dimitrios Kalavrouziotis, Paraskevas Bakopoulos, Elad Mentovich
  • Patent number: 11613565
    Abstract: Disclosed are peptides comprising amino acid residues of the dimer interface of human B7-1 and B7-2 and compositions and uses thereof.
    Type: Grant
    Filed: January 21, 2020
    Date of Patent: March 28, 2023
    Assignee: YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD
    Inventors: Raymond Kaempfer, Revital Levy
  • Publication number: 20230091231
    Abstract: The present disclosure provides, in part, a cell culture medium supplement comprising at least one plant protein homologue of a serum protein, a cell culture medium comprising a serum-free base medium and one or more plant based proteins, and methods of growing cells in vitro and of producing cultured meat using the cell culture medium.
    Type: Application
    Filed: January 20, 2021
    Publication date: March 23, 2023
    Applicants: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd., Future Meat Technologies Ltd.
    Inventors: Yaakov Nahmias, Merav Cohen, Jonathan Caspi
  • Patent number: 11608394
    Abstract: A method for generating reactive species in a medium in which light irradiates the medium including a nanoparticle. A photoinitiator composed of semiconductor nanoparticles for photo-polymerization and 2D and 3D printing.
    Type: Grant
    Filed: February 6, 2019
    Date of Patent: March 21, 2023
    Assignee: YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD.
    Inventors: Uri Banin, Shlomo Magdassi, Nir Waiskopf, Lior Efraim Verbitsky
  • Publication number: 20230080018
    Abstract: The invention provides a method for lubricating one or more surfaces, comprising applying gel-phase liposomes onto said one or more surfaces, wherein the temperature of said surface(s) at the time of lubrication is below the phase transition temperature Tm of said liposomes. The method can be used for lubricating non-biological surfaces, and also for lubricating the surfaces of a biological tissue in a mammalian subject, e.g., for treating joint dysfunction.
    Type: Application
    Filed: November 10, 2022
    Publication date: March 16, 2023
    Applicants: YEDA RESEARCH AND DEVELOPMENT CO., LTD., YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM, LT
    Inventors: Jacob KLEIN et al., Ronit Goldberg, Yechezkel Barenholtz, Avi Schroeder
  • Publication number: 20230076173
    Abstract: The present invention provides antimicrobial matrices comprising a water-insoluble polymer and a mixture comprising a plurality of synthetic peptides attached thereto via a linker, the peptides comprise cationic amino acid residues, hydrophobic amino acid residues, or combinations thereof, in random sequences. The invention further provides uses of the antimicrobial matrices for eliminating microorganisms, particularly pathogenic bacteria, from liquid or semi solid media including edible products or beverages.
    Type: Application
    Filed: February 9, 2021
    Publication date: March 9, 2023
    Applicant: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventor: Zvi HAYOUKA
  • Publication number: 20230070582
    Abstract: The present disclosure provides, in part, a cell culture medium comprising a serum-free medium and one or more fibroblast growth factor (FGF) activators, a kit comprising the cell culture medium and instructions for use, methods of growing cells in vitro and of producing a cultured meat using the cell culture medium, and a cultured meat so produced.
    Type: Application
    Filed: January 20, 2021
    Publication date: March 9, 2023
    Applicant: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Yaakov Nahmias, Muneef Ayyash, Laura Pasitka
  • Publication number: 20230073614
    Abstract: The present disclosure provides, in part, a receptacle for filtering a liquid. The receptacle comprises a plurality of hollow fibers extending the length of the receptacle and at least one solid absorbent material occupying a space between the plurality of hollow fibers. Each hollow fiber comprises at least one opening and a lumen defined by the walls thereof, allowing the liquid to flow through. The hollow fiber walls have a porosity profile selective to passage of waste materials contained in the liquid from the lumen to the solid absorbent material(s), thereby filtering the liquid. Also provided is a system as well as a method for filtering and recycling a cell culture medium.
    Type: Application
    Filed: January 29, 2021
    Publication date: March 9, 2023
    Applicants: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd., Future Meat Technologies Ltd.
    Inventors: Yaakov Nahmias, Guy Wissotsky
  • Publication number: 20230048027
    Abstract: A composition for reducing the weight loss and/or preserving the natural gloss of post-harvest edible plant matter, and methods for applying the compositions to the surface of the plant matter. The compositions include an edible wax having a melting temperature below 70° C.; a hydrocolloid; a fatty acid; an emulsifier; and water, wherein the edible wax is present in a weight percent ranging from about 10% to about 25% of the total weight of the composition.
    Type: Application
    Filed: September 9, 2022
    Publication date: February 16, 2023
    Applicant: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Amos NUSSINOVITCH, Tal MARMUR, Yonatan ELKIND
  • Patent number: 11564408
    Abstract: The present invention provides processes for producing food products, particularly juice beverages, with reduced sugar content enriched with dietary fibers and the food products produced. The processed food products are low in calories while preserving the palatable test of the starting material, and contain beneficial amount of dietary fibers. The processed food product further contains sorbitol and gluconic acid.
    Type: Grant
    Filed: October 25, 2017
    Date of Patent: January 31, 2023
    Assignee: YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD.
    Inventors: Roni Shapira, Eran Balachinsky
  • Patent number: 11560417
    Abstract: Isolated polypeptides of CD44 are provided. Accordingly, there is provided an isolated polypeptide consisting of an amino acid sequence selected from the group consisting of SEQ ID NOs: 1-3. Also provided is an isolated end-capping modified polypeptide comprising an amino acid sequence selected from the group consisting of SEQ ID NO: 1-3, wherein the modified polypeptide comprises an anti-inflammatory activity. Also provided are compositions of matter, fusion proteins and pharmaceutical compositions and their use in the treatment of inflammatory disease.
    Type: Grant
    Filed: February 18, 2020
    Date of Patent: January 24, 2023
    Assignee: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: David Naor, Lora Eshkar-Sebban, Keren-Or Amar, Shmuel Cohen