Patents Assigned to HELION BIOTECH APS
  • Antibodies to MASP-2
    Patent number: 11225526
    Abstract: The invention relates to antibodies to MASP-2 and functional equivalents thereof. In particular, the invention relates to MASP-2 antibodies capable of inhibiting the function of MASP-2. The invention furthermore discloses MASP-2 epitopes, wherein antibodies recognising said epitopes are in particularly useful for inhibiting MASP-2 activity. The invention also relates to methods of producing said antibodies, methods of inhibiting MASP-2 activity as well as to pharmaceutical compositions comprising the MASP-2 antibodies.
    Type: Grant
    Filed: February 22, 2021
    Date of Patent: January 18, 2022
    Assignee: Helion Biotech ApS
    Inventors: Flemming Larsen, Ulla Wahlers
  • Antibodies to MASP-2
    Patent number: 11008405
    Abstract: The invention relates to antibodies to MASP-2 and functional equivalents thereof. In particular, the invention relates to MASP-2 antibodies capable of inhibiting the function of MASP-2. The invention furthermore discloses MASP-2 epitopes, wherein antibodies recognising said epitopes are in particularly useful for inhibiting MASP-2 activity. The invention also relates to methods of producing said antibodies, methods of inhibiting MASP-2 activity as well as to pharmaceutical compositions comprising the MASP-2 antibodies.
    Type: Grant
    Filed: January 7, 2020
    Date of Patent: May 18, 2021
    Assignee: Helion Biotech ApS
    Inventors: Flemming Larsen, Ulla Wahlers
  • Antibodies to MASP-2
    Patent number: 11008404
    Abstract: The invention relates to antibodies to MASP-2 and functional equivalents thereof. In particular, the invention relates to MASP-2 antibodies capable of inhibiting the function of MASP-2. The invention furthermore discloses MASP-2 epitopes, wherein antibodies recognising said epitopes are in particularly useful for inhibiting MASP-2 activity. The invention also relates to methods of producing said antibodies, methods of inhibiting MASP-2 activity as well as to pharmaceutical compositions comprising the MASP-2 antibodies.
    Type: Grant
    Filed: December 4, 2018
    Date of Patent: May 18, 2021
    Assignee: Helion Biotech ApS
    Inventors: Flemming Larsen, Ulla Wahlers
  • Antibodies to MASP-2
    Patent number: 10189909
    Abstract: The invention relates to antibodies to MASP-2 and functional equivalents thereof. In particular, the invention relates to MASP-2 antibodies capable of inhibiting the function of MASP-2. The invention furthermore discloses MASP-2 epitopes, wherein antibodies recognizing said epitopes are in particularly useful for inhibiting MASP-2 activity. The invention also relates to methods of producing said antibodies, methods of inhibiting MASP-2 activity as well as to pharmaceutical compositions comprising the MASP-2 antibodies.
    Type: Grant
    Filed: June 19, 2015
    Date of Patent: January 29, 2019
    Assignee: Helion Biotech ApS
    Inventors: Flemming Larsen, Ulla Wahlers
  • MASP-2, a complement fixing enzyme, and uses for it
    Patent number: 9441262
    Abstract: The invention relates to the discovery and characterization of mannan binding lectin-associated serine protease-2 (MASP-2), a new serine protease that acts in the MBLectin complement fixation pathway.
    Type: Grant
    Filed: September 19, 2013
    Date of Patent: September 13, 2016
    Assignee: Helion Biotech ApS
    Inventors: Jens Chr. Jensenius, Steffen Thiel
  • Antibodies to MASP-2
    Patent number: 9096676
    Abstract: The invention relates to antibodies to MASP-2 and functional equivalents thereof. In particular, the invention relates to MASP-2 antibodies capable of inhibiting the function of MASP-2. The invention furthermore discloses MASP-2 epitopes, wherein antibodies recognizing said epitopes are in particularly useful for inhibiting MASP-2 activity. The invention also relates to methods of producing said antibodies, methods of inhibiting MASP-2 activity as well as to pharmaceutical compositions comprising the MASP-2 antibodies.
    Type: Grant
    Filed: May 12, 2004
    Date of Patent: August 4, 2015
    Assignee: Helion Biotech APS
    Inventors: Flemming Larsen, Ulla Wahlers
  • MASP-2, A COMPLEMENT FIXING ENZYME, AND USES FOR IT
    Publication number: 20140134641
    Abstract: The invention relates to the discovery and characterization of mannan binding lectin-associated serine protease-2 (MASP-2), a new serine protease that acts in the MBLectin complement fixation pathway.
    Type: Application
    Filed: September 19, 2013
    Publication date: May 15, 2014
    Applicant: Helion Biotech ApS
    Inventors: Jens Chr. Jensenius, Steffen Thiel
  • MASP 2, a complement-fixing enzyme, and uses for it
    Patent number: 8551790
    Abstract: The invention relates to the discovery and characterization of mannan binding lectin-associated serine protease-2 (MASP-2), a new serine protease that acts in the MBLectin complement fixation pathway.
    Type: Grant
    Filed: January 26, 2012
    Date of Patent: October 8, 2013
    Assignee: Helion Biotech ApS
    Inventors: Jens Chr. Jensenius, Steffen Thiel
  • MASP 2, A COMPLEMENT-FIXING ENZYME, AND USES FOR IT
    Publication number: 20120219965
    Abstract: The invention relates to the discovery and characterization of mannan binding lectin-associated serine protease-2 (MASP-2), a new serine protease that acts in the MBLectin complement fixation pathway.
    Type: Application
    Filed: January 26, 2012
    Publication date: August 30, 2012
    Applicant: HELION BIOTECH APS
    Inventors: Jens Chr. Jensenius, Steffen Thiel