Abstract: The invention relates to optical systems and methods for measurement of samples in multiple sample vessels using an array of light sources where the light from the light sources is divided into multiple light beams, and each beam is directed to a sample vessel.
Abstract: Disclosed herein is a microplate comprising a plurality of wells and methods and systems comprising such microplates, wherein an individual well comprises an opaque or non-transparent surface at or near the bottom of the well. The microplates herein can provide improved visualization of the process of filling a well with a liquid reagent. The microplates can be configured to perform chemical analysis, such as polymerase chain reaction (PCR) or nucleic acid detection.
Type:
Grant
Filed:
September 22, 2009
Date of Patent:
October 11, 2011
Assignee:
Helixis, Inc.
Inventors:
Arkadiy Silbergleit, Adrian Fawcett, Michael Andrew Swartz, Kevin Daley Simmons
Abstract: Optical systems, and corresponding methods, for multiple reactions are provided. The optical systems are in a fixed position relative to a thermal assembly and include at least one array of excitation sources (e.g., light emitting diodes (LEDs)) configured to output excitation energy along an excitation optical path. In addition, a detector configured to receive emission energy along a detection optical path in the same plane as the excitation optical path is also provided.
Type:
Application
Filed:
July 22, 2010
Publication date:
March 10, 2011
Applicant:
HELIXIS, INC.
Inventors:
Adrian Fawcett, David Tracy, Kevin Daley Simmons
Abstract: This invention provides a systems and methods for regulating temperature and heat transfer in applications in which it is desirable to maintain temperature uniformity such as thermal cycling applications. A heat block is used to rapidly transfer heat to or from a set of one or more reaction vessels.
Type:
Application
Filed:
April 2, 2010
Publication date:
November 4, 2010
Applicant:
HELIXIS, INC.
Inventors:
George Maltezos, Adrian Fawcett, Matthew Johnston, Xing Yang, David Tracy