Patents Assigned to Hellenic Pasteur Institute
  • Patent number: 8614068
    Abstract: The present invention provides a novel method for producing biologically functional hepcidin in Pichia pastoris. The invention further provides novel tagged hepcidin, antibodies and their uses in therapy and immunoassays.
    Type: Grant
    Filed: August 22, 2008
    Date of Patent: December 24, 2013
    Assignees: Hellenic Pasteur Institute
    Inventors: Avgi Mamalaki, Martha Marinou, Vasiliki Koliaraki
  • Publication number: 20110097749
    Abstract: The present invention provides a novel method for producing biologically functional hepcidin in Pichia pastoris. The invention further provides novel tagged hepcidin, antibodies and their uses in therapy and immunoassays.
    Type: Application
    Filed: August 22, 2008
    Publication date: April 28, 2011
    Applicants: HELLENIC PASTEUR INSTITUTE
    Inventors: Avgi Mamalaki, Martha Marinou, Vasiliki Koliaraki
  • Publication number: 20100047230
    Abstract: The present invention describes an isolated antibody or a fragment, variant or derivative thereof, capable of specifically binding to Her2/neu comprising a heavy chain variable domain wherein said heavy chain variable domain comprises an amino acid sequence as set out in at least one of SEQ ID NOs: 1, 2 or 3 or a sequence having at least 75% identity (homology) thereto or a functional fragment thereof as well as nucleic acid sequences encoding the same and methods for their production. The invention also relates to a method for the treatment of Her2/neu expressing cancer in a patient comprising administering to the patient in need of such treatment a therapeutically effective amount of any of those antibody, polypeptide or nucleic acid molecules described herein.
    Type: Application
    Filed: February 20, 2006
    Publication date: February 25, 2010
    Applicant: HELLENIC PASTEUR INSTITUTE
    Inventors: Avgi Mamalaki, Maria Belimezi, Danai Papanastassiou, Efrossini Merkouri, Konstantinos Baxevanis
  • Publication number: 20090087832
    Abstract: DNA encoding core+1 polypeptides of hepatitis C virus (HCV), nucleotides encoding the polypeptides, and methods for using the nucleotides and the encoded polypeptides are disclosed.
    Type: Application
    Filed: April 13, 2007
    Publication date: April 2, 2009
    Applicants: Institut Pasteur, Hellenic Pasteur Institute
    Inventors: Penelope Mavromara, Agoritsa Varaklioto, Urania Georgopoulou
  • Patent number: 7217801
    Abstract: DNA encoding core+1 polypeptides of hepatitis C virus (HCV), nucleotides encoding the polypeptides, and methods for using the nucleotides and the encoded polypeptides are disclosed.
    Type: Grant
    Filed: September 17, 2003
    Date of Patent: May 15, 2007
    Assignees: Institute Pasteur, Hellenic Pasteur Institute
    Inventors: Penelope Mavromara, Agoritsa Varaklioto, Urania Georgopoulou
  • Patent number: 6803214
    Abstract: DNA encoding core+1 polypeptides of hepatitis C virus (HCV), nucleotides encoding the polypeptides, and methods for using the nucleotides and the encoded polypeptides are disclosed.
    Type: Grant
    Filed: August 24, 2000
    Date of Patent: October 12, 2004
    Assignees: Institut Pasteur, Hellenic Pasteur Institute
    Inventors: Penelope Mavromara, Agoritsa Varaklioto, Urania Georgopoulou