Patents Assigned to Helmholtz Center for Infection Research
  • Hepatitis C virus immunogenic compositions and methods of use thereof
    Patent number: 12042536
    Abstract: The present disclosure provides immunogenic compositions comprising: a) hepatitis C virus (HCV) E1E2 heterodimers, HCV E2, or HCV E1; and b) an adjuvant, where the adjuvant is a cyclic dinucleotide or an archaeosome. The present disclosure provides methods of inducing an immune response in an individual to HCV, the methods comprising administering to an individual an effective amount of an immunogenic composition of the present disclosure.
    Type: Grant
    Filed: January 19, 2023
    Date of Patent: July 23, 2024
    Assignees: The Governors of the University of Alberta, Helmholtz Center for Infection Research
    Inventors: Michael Houghton, Abdolamir Landi, Carlos A. Guzman, Thomas Ebensen, Darren Hockman, John L. Law, Michael Logan
  • Hepatitis C virus immunogenic compositions and methods of use thereof
    Patent number: 10881726
    Abstract: The present disclosure provides immunogenic compositions comprising: a) hepatitis C virus (HCV) E1E2 heterodimers, HCV E2, or HCV E1; and b) an adjuvant, where the adjuvant is a cyclic dinucleotide or an archaeosome. The present disclosure provides methods of inducing an immune response in an individual to HCV, the methods comprising administering to an individual an effective amount of an immunogenic composition of the present disclosure.
    Type: Grant
    Filed: October 5, 2017
    Date of Patent: January 5, 2021
    Assignees: The Governors of the University of Alberta, Helmholtz Center for Infection Research
    Inventors: Michael Houghton, Abdolamir Landi, Carlos A. Guzman, Thomas Ebensen, Darren Hockman, John L. Law, Michael Logan
  • Triazolo-epothilones
    Patent number: 7419993
    Abstract: The invention relates to triazolo-thiazole analogues of epothilone A and epothilone B.
    Type: Grant
    Filed: February 9, 2005
    Date of Patent: September 2, 2008
    Assignee: Helmholtz Center of Infection Research GmbH
    Inventors: Gerhard Hoefle, Nicole Glaser