Abstract: The present invention provides means and methods for selectively detecting activated MALT1 in a sample. Moreover, the present invention provides a method for diagnosing diseases, which are characterized by an increased MALT1 activity. Finally, the present invention provides methods for identifying patients which are amenable to treatment with a therapeutic agent capable of inhibiting MALT1 activity.
Type:
Grant
Filed:
January 20, 2015
Date of Patent:
December 10, 2019
Assignees:
Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umweld (GmbH), Technische Universität München
Inventors:
Daniel Krappmann, Andrea Eitelhuber, Steven Verhelst