Patents Assigned to Helmholtz Zentrum München Deutsches Forschungszentrym für Gesundheit und Umwelt (Gmbh)
  • Compositions for the preparation of mature dendritic cells
    Patent number: 8679840
    Abstract: The invention relates to a method for in vitro maturation of at least one immature dendritic cell, comprising stimulating said immature dendritic cell with TNF?, IL- 1?, IFN?, a TLR7/8 agonist and prostaglandin E2 (PG). Furthermore, the invention relates to a composition comprising these factors as well as to mature dendritic cells produced by a method of the invention.
    Type: Grant
    Filed: March 28, 2007
    Date of Patent: March 25, 2014
    Assignee: Helmholtz Zentrum München Deutsches Forschungszentrym für Gesundheit und Umwelt (Gmbh)
    Inventors: Dolores J. Schendel, Anke Zobywalski, Iris Bigalke