Patents Assigned to HELSINGIN YLIOPISTO
  • Publication number: 20230360160
    Abstract: Machine learning based forest management is disclosed. A set of input data related to a forest stand is accessed. A forest management plan defining at least one forest management activity for the forest stand is determined based on the accessed set of input data and at least one forest management preference. The determining of the forest management plan for the forest stand is performed by applying a parameterized policy to the accessed set of input data. The parameterized policy has been trained via a machine learning process using a forest development related simulation model.
    Type: Application
    Filed: September 29, 2021
    Publication date: November 9, 2023
    Applicants: AALTO UNIVERSITY FOUNDATION SR, HELSINGIN YLIOPISTO
    Inventors: Philipp BACK, Antti SUOMINEN, Pekka MALO, Olli TAHVONEN
  • Patent number: 11549200
    Abstract: According to an example aspect of the present invention, there is provided A process for making a cellulose fibre or film comprising the steps of dissolving pulp in an ionic liquid containing a cationic 1,5,7-triazabicyclo[4.4.0]dec-5-enium [TBDH]+ moiety and an anion selected from the group according to Formula a), Formula b) and Formula c), wherein each of R, R2, R3, R4, R5, R7, R8, R9 and R10 is H or an organyl radical and X? is selected from the group consisting of halides, pseudohalides, carboxylates, alkyl sulphite, alkyl sulphate, dialkylphosphite, dialkyl phosphate, dialkyl phosphonites and dialkyl phosphonates, to provide a spinning dope, extruding the spinning dope through a spinneret to form one or more filaments, and a step selected from the group consisting of spinning cellulose fibres from the solution, and extruding a cellulose film from the solution.
    Type: Grant
    Filed: January 30, 2018
    Date of Patent: January 10, 2023
    Assignees: Aalto University Foundation sr, Helsingin Yliopisto
    Inventors: Herbert Sixta, Michael Hummel, Kadvaël Le Boulch, Ilkka Kilpeläinen, Alistair W.T. King, Jussi Helminen, Sanna Hellsten
  • Publication number: 20220041665
    Abstract: A polynucleotide encoding a degradation signal peptide is disclosed. The polynucleotide may comprise a nucleotide sequence encoding a degradation signal peptide, wherein the degradation signal peptide has an amino acid sequence comprising a sequence that is at least 75% identical to a sequence corresponding to amino acid residues 84-98 of SEQ ID NO: 1 (AtIAA7), 66-80 of SEQ ID NO: 2 (AtIAA3), 84-98 of SEQ ID NO: 3 (AtIAA17), 78-92 of SEQ ID NO: 4 (AtIAA14), 55-69 of SEQ ID NO: 5 (AtIAA5), or 167-181 of SEQ ID NO: 6 (AtIAA8), or a degradation signal peptide functionally and/or structurally equivalent thereto.
    Type: Application
    Filed: March 26, 2020
    Publication date: February 10, 2022
    Applicant: Helsingin yliopisto
    Inventors: Shiqian LI, Elina IKONEN
  • Patent number: 11130763
    Abstract: The present invention relates to a method of producing a bicyclic guanidine and its derivatives. In particular, the present invention relates to a method of producing triazabicyclodecene (TBD) and its derivatives, particularly alkyl derivatives, such as methyl triazabicyclodecene (MTBD), and MTBD-derived ionic liquids. The invention also relates to the use of said compounds in cellulose dissolution and subsequent processing.
    Type: Grant
    Filed: November 8, 2018
    Date of Patent: September 28, 2021
    Assignee: Helsingin Yliopisto
    Inventors: Jussi Helminen, Alistair King, Ilkka Kilpeläinen
  • Patent number: 11052245
    Abstract: The present invention relates to a device exploiting magneto-hydrodynamics (MHD) for localized delivery of material into a target or extraction of material from a target. The device includes a frame (101) comprising a space (102) for conductive fluid and the material, at least one pair of electrodes (103A, 103B) facing each other, a source of electric current (105), a magnet (105), and an opening (106). The electric current and the magnetic field are synchronized so that the material can be moved from the volume between the electrodes through the opening towards the target or from the target through the opening towards the volume. According to the invention the volume is ?2000 mm3, in proviso that mean distance between tips of the electrodes is ?20 mm.
    Type: Grant
    Filed: July 2, 2016
    Date of Patent: July 6, 2021
    Assignee: HELSINGIN YLIOPISTO
    Inventors: Alejandro Garcia Perez, Heikki Juhani Nieminen, Aino Tietäväinen, Edward Haeggström
  • Publication number: 20210181391
    Abstract: A field-enhancing device includes at least one metal layer or a metal grating consisting of metal stripes or a dielectric grating. Usually the device is constructed on some substrate. The adhesive layer is advantageous when the next layer is metallic but is not needed with dielectric layers. The next layers to be constructed form a mirror structure that can also be omitted for simple field-enhancing device constructs. The mirror structure can be either a metal mirror structure or a distributed Bragg reflector structure (DBR). The next layer is the thin metal layer. This layer can be covered with a 1-D metal grating consisting of metal stripes or with a dielectric grating having similar geometry. The structure can also be fabricated without metals when dielectric grating is used as the field-enhancing part. Finally, a protective layer can be added on top of the structure.
    Type: Application
    Filed: November 6, 2018
    Publication date: June 17, 2021
    Applicants: Aalto University Foundation sr, Helsingin yliopisto
    Inventors: Nagarajan Subramaniyam, Markku SOPANEN, Elina IKONEN, Antti ISOMÄKI, Simon PFISTERER
  • Patent number: 10649186
    Abstract: The invention relates to a mobile microscopic imaging device comprising a sample stage for holding a sample to be imaged, at least one light source for illumination of the sample, an imaging panel capable of capturing an image of the sample upon transmission illumination of the sample by the light source, and an optical magnification unit between the sample and the imaging panel for guiding light from the illuminated sample to the imaging panel so that a magnified image of at least portion of the sample is formed at the imaging panel. According to the invention, the optical magnification unit comprises a filter integrated polymeric lens assembly in a transmitted light fluorescence configuration which allows for both miniaturization of the device to a truly mobile level and reducing manufacturing costs.
    Type: Grant
    Filed: August 26, 2016
    Date of Patent: May 12, 2020
    Assignee: HELSINGIN YLIOPISTO
    Inventors: Johan Lundin, Antti Suutala, Hannu Moilanen
  • Patent number: 10436934
    Abstract: Disclosed is a method for generating an estimation of earth's gravity. The method includes: obtaining one or more acceleration data values and one or more orientation data values over a period of time; generating magnitude of orientation change from the orientation data values; determining a stability value based on the acceleration data values and the magnitude of orientation change; comparing the determined stability value to a threshold value; and generating an estimation of earth's gravity over the period of time on the basis of the acceleration data values if the comparison indicates that the determined stability value is below the threshold value. Also disclosed is an apparatus implementing the method.
    Type: Grant
    Filed: June 30, 2015
    Date of Patent: October 8, 2019
    Assignee: HELSINGIN YLIOPISTO
    Inventors: Samuli Hemminki, Petteri Nurmi, Sasu Tarkoma
  • Patent number: 10240259
    Abstract: A method of manufacturing a cellulose-based shaped article. The method comprises subjecting a solution of lignocellulosic material, dissolved in a distillable ionic liquid, to a spinning method, wherein the ionic liquid is a diazabicyclononene (DBN)-based ionic liquid. DBN-based ionic liquids have good dissolution power, high thermal and chemical stability, lack runaway reactions and exhibit low energy consumption, due to low spinning temperatures. The shaped cellulose articles can be used as textile fibers, high-end non-woven fibers, technical fibers, films for packaging, and barriers films in batteries, as membranes and as carbon-fiber precursors.
    Type: Grant
    Filed: April 4, 2014
    Date of Patent: March 26, 2019
    Assignees: Aalto University Foundation sr, Helsingin Yliopisto
    Inventors: Anne Michud, Alistair W. T. King, Arno Parviainen, Herbert Sixta, Lauri Hauru, Michael Hummel, Iikka Kilpeläinen
  • Patent number: 10234266
    Abstract: A method for calibrating electromagnetic radiation-based three-dimensional imaging includes: obtaining (501) a calibration imaging result at least partly on the basis of electromagnetic waves received from a calibration artifact, forming (502) calibration data on the basis of the calibration imaging result and a known thickness profile of the calibration artifact, and correcting (503), with the aid of the calibration data, an imaging result obtained at least partly on the basis of electromagnetic waves received from a sample to be imaged. The calibration artifact includes layers, for example Langmuir-Blodgett films, having pre-determined thicknesses and stacked on each other so as to achieve the pre-determined thickness profile of the calibration artifact. A three-dimensional imaging system configured to carry out the method.
    Type: Grant
    Filed: October 29, 2015
    Date of Patent: March 19, 2019
    Assignees: ABO AKADEMI (ABO AKADEMI UNIVERSITY), HELSINGIN YLIOPISTO
    Inventors: Edward Hæggstrom, Ivan Kassamakov, Anton Nolvi, Tuomo Ylitalo, Niklas Sandler, Tapani Viitala, Johan Nyman
  • Publication number: 20180221656
    Abstract: The present invention relates to a device exploiting magneto-hydrodynamics (MHD) for localized delivery of material into a target or extraction of material from a target. The device includes a frame (101) comprising a space (102) for conductive fluid and the material, at least one pair of electrodes (103A, 103B) facing each other, a source of electric current (105), a magnet (105), and an opening (106). The electric current and the magnetic field are synchronized so that the material can be moved from the volume between the electrodes through the opening towards the target or from the target through the opening towards the volume. According to the invention the volume is?2000 mm3, in proviso that mean distance between tips of the electrodes is?20 mm.
    Type: Application
    Filed: July 2, 2016
    Publication date: August 9, 2018
    Applicant: Helsingin Yliopisto
    Inventors: Alejandro GARCIA PEREZ, Heikki Juhani NIEMINEN, Aino TIETÄVÄINEN, Edward HAEGGSTRÖM
  • Patent number: 9994899
    Abstract: This invention relates to a quantitative method for determining whether a human subject has an impaired DNA mismatch repair function; providing a diagnostic sample taken from said human and producing a nuclear extract from said sample; providing MMR proficient and MMR deficient nuclear extracts as positive and negative controls, respectively; combining each nuclear extract with at least one mismatch bearing substrate DNA molecule; performing a mismatch repair assay; and determining whether said sample nuclear extract is capable of repairing said substrate DNA molecule; wherein said sample comprises normal, non-malignant constitutive cells, such as fibroblasts. The invention further relates to a kit providing necessary reagents for use in said method.
    Type: Grant
    Filed: June 29, 2012
    Date of Patent: June 12, 2018
    Assignee: HELSINGIN YLIOPISTO
    Inventors: Minna Nyström, Minttu Kansikas, Päivi Peltomäki
  • Patent number: 9944908
    Abstract: The present invention relates to a polypeptide, or a fragment thereof, capable of enhancing callose biosynthesis and/or accumulation, wherein at least one of the conserved amino acid residues selected from the group consisting of residue corresponding to R84 of SEQ ID NO: 1, residue corresponding to R1926 or SEQ ID NO: 1 and residue corresponding to P189 of SEQ ID NO: 1, of the polypeptide or a fragment thereof, is modified by a mutation selected from the group consisting of substitution and deletion.
    Type: Grant
    Filed: November 29, 2012
    Date of Patent: April 17, 2018
    Assignee: HELSINGIN YLIOPISTO
    Inventors: Anne Vatèn, Jan Dettmer, Shunsuke Miyashima, Shri Ram Yadav, Ana Campilho, Vincent Bulone, Raffael Lichtenberger, Satu Lehesranta, Ari Pekka Mähönen, Annelie Carlsbecker, Yrjö Helariutta, Kaori Furuta
  • Publication number: 20180073165
    Abstract: The present invention relates to a device and a method for producing polymer fibers, in particular to nozzle-less electrospinning devices and methods to produce fibers and constructs thereof, wherein the nanofibers are generated by using pulsed and/or bursted ultrasound.
    Type: Application
    Filed: March 19, 2016
    Publication date: March 15, 2018
    Applicant: Helsingin Yliopisto
    Inventors: Ivo LAIDMÄE, Heikki NIEMINEN, Ari SALMI, Tor PAULIN, Timo RAUHALA, Kai FALCK, Jouko YLIRUUSI, Jyrki HEINÄMÄKI, Edward HAEGGSTRÖM, Peep VESKI
  • Publication number: 20140220559
    Abstract: This invention relates to a quantitative method for determining whether a human subject has an impaired DNA mismatch repair function; providing a diagnostic sample taken from said human and producing a nuclear extract from said sample; providing MMR proficient and MMR deficient nuclear extracts as positive and negative controls, respectively; combining each nuclear extract with at least one mismatch bearing substrate DNA molecule; performing a mismatch repair assay; and determining whether said sample nuclear extract is capable of repairing said substrate DNA molecule; wherein said sample comprises normal, non-malignant constitutive cells, such as fibroblasts. The invention further relates to a kit providing necessary reagents for use in said method.
    Type: Application
    Filed: June 29, 2012
    Publication date: August 7, 2014
    Applicant: HELSINGIN YLIOPISTO
    Inventors: Minna Nyström, Minttu Kansikas, Päivi Peltomäki
  • Publication number: 20100159093
    Abstract: The present invention relates to a method of improving the safety, the quality and the durability of foodstuffs and raw materials which are used in the production of foodstuffs, and to a foodstuff or a foodstuff raw material. A foodstuff or a foodstuff raw material is treated with pure nitrogen gas in order to prevent the growth of microbes in the foodstuff or the foodstuff raw material. The nitrogen gas method according to the present invention makes it possible to eliminate efficiently the bacteria which produce large quantities of phospholipase from the foodstuff or the foodstuff raw material. The nitrogen gas method is especially suitable for the treatment of milk products, particularly raw milk.
    Type: Application
    Filed: June 13, 2008
    Publication date: June 24, 2010
    Applicant: Helsingin Yliopisto
    Inventors: Tapani Alatossava, Patricia Munsch-Alatossava
  • Publication number: 20080165354
    Abstract: The invention concerns a method and apparatus for monitoring physical and chemical properties of a solid sample during a dissolution process, the sample comprising at least one soluble component. In the method, the solid sample is brought into contact with dissolution medium for producing a solution and a solid residue of the solid sample, the solution is analyzed for determining the concentration of the soluble component during the dissolution process. Simultaneously with analyzing the solution, the atom- or molecule-scale physical or chemical composition of the solid residue is analyzed. The invention provides a new method for studying phenomena taking place in the solid residue during a dissolution process.
    Type: Application
    Filed: April 10, 2006
    Publication date: July 10, 2008
    Applicant: HELSINGIN YLIOPISTO
    Inventors: Jukka Rantanen, Jaakko Aaltonen, Jouni Hirvonen, Leena Peltonen