Patents Assigned to Helwan University
  • Aryl-1,2,3-triazole compounds, pharmaceutical composition thereof and method for treatment of breast cancer
    Patent number: 12258321
    Abstract: Compounds belonging to the group of N-benzyl-2-(4-(4-substituted-1H-1,2,3-triazol-1-yl)phenylacetamides have cytotoxic activities against MCF7 breast cancer cells, and are useful in therapeutic regimes for breast cancer. The N-benzyl-2-(4-(4-substituted-1H-1,2,3-triazol-1-yl)phenylacetamides also have beneficial effects on BAX, BCL-2, MCL-1 and MAPK pathways within MCF& breast cancer cells.
    Type: Grant
    Filed: October 14, 2024
    Date of Patent: March 25, 2025
    Assignees: University of Jeddah, King Abdulaziz University, Helwan University
    Inventors: Roaa M. Alreemi, Hind A. Alkhatabi, Mohammed A. Baradwan, Abdelsattar M. Omar, Moustafa E. El-Araby, Yara E. Mansour, Samar S. Fatahala, Ahmed M. Said, Shahenda Mahgoub