Abstract: The present disclosure relates to methods for treating blood transfusion-dependent hematological malignancy patients with oxygen reduced blood.
Type:
Application
Filed:
October 20, 2023
Publication date:
May 28, 2026
Applicant:
Hemanext Inc.
Inventors:
Martin CANNON, Andrew DUNHAM, Laurel OMERT, Kimberly DORSCH, Michael DIOGUARDI
Abstract: The present disclosure relates to Oxygen Reduction Disposable kits (ORDKit), devices and methods for the improved preservation of whole blood and blood components. The improved devices and methods for the collection of blood and blood components provide for whole blood and blood components having reduced levels of oxygen. The devices and methods provide for the rapid preparation of deoxygenated blood and blood components for storage that improves the overall quality of the transfused blood and improves health outcomes in patients.
Type:
Grant
Filed:
April 7, 2023
Date of Patent:
April 21, 2026
Assignee:
Hemanext Inc.
Inventors:
Michael Wolf, Jancarlo Sarita, Jeffrey Karl Sutton, Rafael Cordero, Michael Zocchi, Philip Keegan, Narendran Renganathan, Robert Harhen
Abstract: Methods for the reversal of hemorrhagic shock or hemorrhagic trauma. Methods for reducing levels of aspartate aminotransferase (AST) and alanine aminotransferase (ALT) in a trauma patient through the administration of stored oxygen reduced blood products.
Abstract: A method for reducing hemolysis and microparticle formation during storage of pathogen reduced blood. Oxygen reduced blood compositions comprising SAGM and riboflavin having reduced hemolysis. Oxygen reduced blood compositions comprising SAGM and riboflavin having reduced microparticles. Oxygen and pathogen reduced blood compositions comprising CPAD and riboflavin having reduced hemolysis. Oxygen and pathogen reduced blood compositions comprising SAGM and riboflavin having reduced microparticles.
Type:
Application
Filed:
June 20, 2025
Publication date:
February 12, 2026
Applicant:
Hemanext Inc.
Inventors:
Samuel O. SOWEMIMO-COKER, Jeffrey SUTTON, Tatsuro YOSHIDA
Abstract: A system and methodology for the preservation of red blood cells is described in which red blood cells are oxygen or oxygen and carbon dioxide depleted, treated and are stored in an anaerobic environment to optimize preparation for transfusion. More particularly, a system and method for extended storage of red blood cells from collection to transfusion that optimizes red blood cells prior to transfusion is described.
Abstract: A blood storage container for the anaerobic storage of blood, having enhanced scaling methods and materials for the preservation of stored blood is provided.
Type:
Application
Filed:
August 29, 2024
Publication date:
August 28, 2025
Applicant:
Hemanext Inc.
Inventors:
Tatsuro YOSHIDA, Rafael CORDERO, Jancarlo SARITA, Michael ZOCCHI, Michael WOLF, Philip Michael KEEGAN, Narendran RENGANATHAN, Jeffrey Karl SUTTON
Abstract: A method for reducing hemolysis and microparticle formation during storage of pathogen reduced blood. Oxygen reduced blood compositions comprising SAGM and riboflavin having reduced hemolysis. Oxygen reduced blood compositions comprising SAGM and riboflavin having reduced microparticles. Oxygen and pathogen reduced blood compositions comprising CPAD and riboflavin having reduced hemolysis. Oxygen and pathogen reduced blood compositions comprising SAGM and riboflavin having reduced microparticles.
Type:
Grant
Filed:
January 19, 2024
Date of Patent:
July 22, 2025
Assignee:
Hemanext Inc.
Inventors:
Samuel O. Sowemimo-Coker, Jeffrey Sutton, Tatsuro Yoshida
Abstract: A blood storage container for the anaerobic storage of blood, having enhanced sealing methods and materials for the preservation of stored blood is provided.
Type:
Grant
Filed:
October 16, 2020
Date of Patent:
January 21, 2025
Assignee:
Hemanext Inc.
Inventors:
Tatsuro Yoshida, Rafael Cordero, Jancarlo Sarita, Michael Zocchi, Michael Wolf, Philip Michael Keegan, Narendran Renganathan, Jeffrey Karl Sutton
Abstract: A blood storage system comprising: a collection vessel for red blood cells; an oxygen or oxygen and carbon dioxide depletion device; a storage vessel for red blood cells; tubing connecting the collection vessel to the oxygen or oxygen and carbon dioxide depletion device and the oxygen or oxygen and carbon dioxide depletion device to the storage vessel; and a gamma or X-ray irradiating device is used to irradiate red blood cells stored in the vessel, storing red blood cells under anaerobic conditions.
Abstract: A blood storage system comprising: a collection vessel for red blood cells; an oxygen or oxygen and carbon dioxide depletion device; a storage vessel for red blood cells; tubing connecting the collection vessel to the oxygen or oxygen and carbon dioxide depletion device and the oxygen or oxygen and carbon dioxide depletion device to the storage vessel; and a gamma or X-ray irradiating device is used to irradiate red blood cells stored in the vessel, storing red blood cells under anaerobic conditions.
Abstract: The present disclosure relates to improved collapsible blood containers comprising reinforced silicone for use in Oxygen Reduction Disposable kits (ORDKit), devices and methods. The improved collapsible blood containers and methods for the collection of blood and blood components provide for improved burst, tear, and puncture resistance.
Type:
Application
Filed:
August 18, 2023
Publication date:
May 16, 2024
Applicant:
Hemanext Inc.
Inventors:
Robert HARHEN, Peter PIGNONE, Narendran RENGANATHAN, Jancarlo SARITA, Jeffrey Karl SUTTON, Michael WOLF, Michael R. ZOCCHI
Abstract: A method for reducing hemolysis and microparticle formation during storage of pathogen reduced blood. Oxygen reduced blood compositions comprising SAGM and riboflavin having reduced hemolysis. Oxygen reduced blood compositions comprising SAGM and riboflavin having reduced microparticles. Oxygen and pathogen reduced blood compositions comprising CPAD and riboflavin having reduced hemolysis. Oxygen and pathogen reduced blood compositions comprising SAGM and riboflavin having reduced microparticles.
Type:
Application
Filed:
January 19, 2024
Publication date:
May 9, 2024
Applicant:
Hemanext Inc.
Inventors:
Samuel O. SOWEMIMO-COKER, Jeffrey SUTTON, Tatsuro YOSHIDA
Abstract: A method for reducing hemolysis and microparticle formation during storage of pathogen reduced blood. Oxygen reduced blood compositions comprising SAGM and riboflavin having reduced hemolysis. Oxygen reduced blood compositions comprising SAGM and riboflavin having reduced microparticles. Oxygen and pathogen reduced blood compositions comprising CPAD and riboflavin having reduced hemolysis. Oxygen and pathogen reduced blood compositions comprising SAGM and riboflavin having reduced microparticles.
Type:
Grant
Filed:
September 23, 2021
Date of Patent:
February 27, 2024
Assignee:
Hemanext Inc.
Inventors:
Samuel O. Sowemimo-Coker, Jeffrey Sutton, Tatsuro Yoshida
Abstract: The present disclosure relates to Oxygen Reduction Disposable kits (ORDKit), devices and methods for the improved preservation of whole blood and blood components. The improved devices and methods for the collection of blood and blood components provide for whole blood and blood components having reduced levels of oxygen. The devices and methods provide for the rapid preparation of deoxygenated blood and blood components for storage that improves the overall quality of the transfused blood and improves health outcomes in patients.
Type:
Application
Filed:
April 7, 2023
Publication date:
August 10, 2023
Applicant:
Hemanext Inc.
Inventors:
Michael WOLF, Jancarlo SARITA, Jeffrey Karl SUTTON, Rafael CORDERO, Michael ZOCCHI, Philip KEEGAN, Narendran RENGANATHAN, Robert HARHEN